inclusion criteria: 1. participants aged 18 years and above at the time of screening. 2. received the 1st booster vaccination at least 180 days earlier. 3. agree to attend all visits and sign the written informed consent form.

inclusion criteria: 1. participants aged 18 years and above at the time of screening. 2. received the 1st booster vaccination at least 180 days earlier. 3. agree to attend all visits and sign the written informed consent form.

inclusion criteria: participants aged 18 years and above at the time of screening. received the 1st booster vaccination at least 180 days earlier. agree to attend all visits and sign the written informed consent form.

inclusion criteria: participants aged 18 years and above at the time of screening. received the 1st booster vaccination at least 180 days earlier. agree to attend all visits and sign the written informed consent form.