inclusion criteria: 1. age at the time of the first dose of vaccine: 18 and above; 2. axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; 3. based on the medical history, physical examination and laboratory examination results, the investigator clinically determined the qualified person. 4. has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: 1. age at the time of the first dose of vaccine: 18 and above; 2. axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; 3. based on the medical history, physical examination and laboratory examination results, the investigator clinically determined the qualified person. 4. has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: 18 and above; axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; based on the medical history, physical examination and laboratory examination results, the investigator clinically determined the qualified person. has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: 18 and above; axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; based on the medical history, physical examination and laboratory examination results, the investigator clinically determined the qualified person. has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: 18 and above; axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; based on medical history, physical examination and laboratory test results, the investigator will clinically determine the physically qualified participants. has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: 18 and above; axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; based on medical history, physical examination and laboratory test results, the investigator will clinically determine the physically qualified participants. has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: 18 and above; axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; based on medical history, physical examination and laboratory test results, the investigator will clinically determine the physically qualified participants. as the general principle, if there are test results beyond the normal range before enrollment: 1) a participant can be enrolled if there is no significant change compared with the previous baseline level when the condition of the participant was stable; or, 2) a participant can be enrolled if the result is in the range of grade 1 (inclusive) standard specified in the guidelines for adverse event classification standards for clinical trials of preventive vaccines (2019) issued by nmpa has independent judgment, and participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: 18 and above; axillary body temperature is less than 37.3 degree centigrade on the day of enrollment; based on medical history, physical examination and laboratory test results, the investigator will clinically determine the physically qualified participants. as the general principle, if there are test results beyond the normal range before enrollment: 1) a participant can be enrolled if there is no significant change compared with the previous baseline level when the condition of the participant was stable; or, 2) a participant can be enrolled if the result is in the range of grade 1 (inclusive) standard specified in the guidelines for adverse event classification standards for clinical trials of preventive vaccines (2019) issued by nmpa has independent judgment, and participate voluntarily and sign an informed consent form.