1. confirmed acute cases of sars-cov-2 infection. 2. have a history of sars, mers infection (self-report, on-site inquiry). 3. positive urine pregnancy test result. 4. fever (body temperature \> 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination. 5. axillary body temperature \> 37.0 ℃ before vaccination. 6. previous severe allergic reactions to vaccination (such as acute allergic reactions, urticaria, dyspnea, angioneurotic edema or abdominal pain) or allergy to known ingredients of inactivated sars-cov-2 vaccine have occurred. 7. has a history of convulsion, epilepsy, encephalopathy or mental illness or family history. 8. with congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. 9. with severe liver diseases, severe kidney diseases defined as egfr less than 60, uncontrollable hypertension (systolic blood pressure \>150 mmhg, diastolic blood pressure \> 90 mmhg), diabetic complications, malignant tumors, various acute diseases, or acute attack period of chronic diseases. 10. has been diagnosed with congenital or acquired immune deficiency, hiv infection, lymphoma, leukemia or other autoimmune diseases. 11. with known or suspected diseases include acute respiratory diseases (e.g. influenza like illness, acute cough, sore throat), severe cardiovascular diseases, liver and kidney diseases, and malignant tumors. 12. has a history of coagulation dysfunction (e.g. coagulation factor deficiency, coagulation disease). 13. receiving anti-tb therapy. 14. patients receiving immunotherapy or inhibitor therapy within 3 months (continuous oral or infusion for more than 14 days). 15. live attenuated vaccine is inoculated within 1 month before this vaccination, other vaccines are inoculated within 14 days before this vaccination. 16. received blood products within 3 months before this vaccination 17. received other research drugs within 6 months before this vaccination. 18. other circumstances judged by investigators that are not suitable for this clinical trial.

1. confirmed acute cases of sars-cov-2 infection. 2. have a history of sars, mers infection (self-report, on-site inquiry). 3. positive urine pregnancy test result. 4. fever (body temperature \> 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination. 5. axillary body temperature \> 37.0 ℃ before vaccination. 6. previous severe allergic reactions to vaccination (such as acute allergic reactions, urticaria, dyspnea, angioneurotic edema or abdominal pain) or allergy to known ingredients of inactivated sars-cov-2 vaccine have occurred. 7. has a history of convulsion, epilepsy, encephalopathy or mental illness or family history. 8. with congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. 9. with severe liver diseases, severe kidney diseases defined as egfr less than 60, uncontrollable hypertension (systolic blood pressure \>150 mmhg, diastolic blood pressure \> 90 mmhg), diabetic complications, malignant tumors, various acute diseases, or acute attack period of chronic diseases. 10. has been diagnosed with congenital or acquired immune deficiency, hiv infection, lymphoma, leukemia or other autoimmune diseases. 11. with known or suspected diseases include acute respiratory diseases (e.g. influenza like illness, acute cough, sore throat), severe cardiovascular diseases, liver and kidney diseases, and malignant tumors. 12. has a history of coagulation dysfunction (e.g. coagulation factor deficiency, coagulation disease). 13. receiving anti-tb therapy. 14. patients receiving immunotherapy or inhibitor therapy within 3 months (continuous oral or infusion for more than 14 days). 15. live attenuated vaccine is inoculated within 1 month before this vaccination, other vaccines are inoculated within 14 days before this vaccination. 16. received blood products within 3 months before this vaccination 17. received other research drugs within 6 months before this vaccination. 18. other circumstances judged by investigators that are not suitable for this clinical trial.

confirmed acute cases of sars-cov-2 infection. have a history of sars, mers infection (self-report, on-site inquiry). positive urine pregnancy test result. fever (body temperature > 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination. axillary body temperature > 37.0 ℃ before vaccination. previous severe allergic reactions to vaccination (such as acute allergic reactions, urticaria, dyspnea, angioneurotic edema or abdominal pain) or allergy to known ingredients of inactivated sars-cov-2 vaccine have occurred. has a history of convulsion, epilepsy, encephalopathy or mental illness or family history. with congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. with severe liver diseases, severe kidney diseases defined as egfr less than 60, uncontrollable hypertension (systolic blood pressure >150 mmhg, diastolic blood pressure > 90 mmhg), diabetic complications, malignant tumors, various acute diseases, or acute attack period of chronic diseases. has been diagnosed with congenital or acquired immune deficiency, hiv infection, lymphoma, leukemia or other autoimmune diseases. with known or suspected diseases include acute respiratory diseases (e.g. influenza like illness, acute cough, sore throat), severe cardiovascular diseases, liver and kidney diseases, and malignant tumors. has a history of coagulation dysfunction (e.g. coagulation factor deficiency, coagulation disease). receiving anti-tb therapy. patients receiving immunotherapy or inhibitor therapy within 3 months (continuous oral or infusion for more than 14 days). live attenuated vaccine is inoculated within 1 month before this vaccination, other vaccines are inoculated within 14 days before this vaccination. received blood products within 3 months before this vaccination received other research drugs within 6 months before this vaccination. other circumstances judged by investigators that are not suitable for this clinical trial.

confirmed acute cases of sars-cov-2 infection. have a history of sars, mers infection (self-report, on-site inquiry). positive urine pregnancy test result. fever (body temperature > 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination. axillary body temperature > 37.0 ℃ before vaccination. previous severe allergic reactions to vaccination (such as acute allergic reactions, urticaria, dyspnea, angioneurotic edema or abdominal pain) or allergy to known ingredients of inactivated sars-cov-2 vaccine have occurred. has a history of convulsion, epilepsy, encephalopathy or mental illness or family history. with congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. with severe liver diseases, severe kidney diseases defined as egfr less than 60, uncontrollable hypertension (systolic blood pressure >150 mmhg, diastolic blood pressure > 90 mmhg), diabetic complications, malignant tumors, various acute diseases, or acute attack period of chronic diseases. has been diagnosed with congenital or acquired immune deficiency, hiv infection, lymphoma, leukemia or other autoimmune diseases. with known or suspected diseases include acute respiratory diseases (e.g. influenza like illness, acute cough, sore throat), severe cardiovascular diseases, liver and kidney diseases, and malignant tumors. has a history of coagulation dysfunction (e.g. coagulation factor deficiency, coagulation disease). receiving anti-tb therapy. patients receiving immunotherapy or inhibitor therapy within 3 months (continuous oral or infusion for more than 14 days). live attenuated vaccine is inoculated within 1 month before this vaccination, other vaccines are inoculated within 14 days before this vaccination. received blood products within 3 months before this vaccination received other research drugs within 6 months before this vaccination. other circumstances judged by investigators that are not suitable for this clinical trial.

1. confirmed acute cases of sars-cov-2 infection. 2. have a history of sars, mers infection (self-report, on-site inquiry). 3. positive urine pregnancy test result. 4. fever (body temperature > 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination. 5. axillary body temperature > 37.0 ℃ before vaccination. 6. previous severe allergic reactions to vaccination (such as acute allergic reactions, urticaria, dyspnea, angioneurotic edema or abdominal pain) or allergy to known ingredients of inactivated sars-cov-2 vaccine have occurred. 7. has a history of convulsion, epilepsy, encephalopathy or mental illness or family history. 8. with congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. 9. with severe liver diseases, severe kidney diseases defined as egfr less than 60, uncontrollable hypertension (systolic blood pressure >150 mmhg, diastolic blood pressure > 90 mmhg), diabetic complications, malignant tumors, various acute diseases, or acute attack period of chronic diseases. 10. has been diagnosed with congenital or acquired immune deficiency, hiv infection, lymphoma, leukemia or other autoimmune diseases. 11. with known or suspected diseases include acute respiratory diseases (e.g. influenza like illness, acute cough, sore throat), severe cardiovascular diseases, liver and kidney diseases, and malignant tumors. 12. has a history of coagulation dysfunction (e.g. coagulation factor deficiency, coagulation disease). 13. receiving anti-tb therapy. 14. patients receiving immunotherapy or inhibitor therapy within 3 months (continuous oral or infusion for more than 14 days). 15. live attenuated vaccine is inoculated within 1 month before this vaccination, other vaccines are inoculated within 14 days before this vaccination. 16. received blood products within 3 months before this vaccination 17. received other research drugs within 6 months before this vaccination. 18. other circumstances judged by investigators that are not suitable for this clinical trial.

1. confirmed acute cases of sars-cov-2 infection. 2. have a history of sars, mers infection (self-report, on-site inquiry). 3. positive urine pregnancy test result. 4. fever (body temperature > 37.0 ℃), dry cough, fatigue, nasal obstruction, runny nose, pharyngeal pain, myalgia, diarrhea, shortness of breath and dyspnea occurred within 14 days before vaccination. 5. axillary body temperature > 37.0 ℃ before vaccination. 6. previous severe allergic reactions to vaccination (such as acute allergic reactions, urticaria, dyspnea, angioneurotic edema or abdominal pain) or allergy to known ingredients of inactivated sars-cov-2 vaccine have occurred. 7. has a history of convulsion, epilepsy, encephalopathy or mental illness or family history. 8. with congenital malformations or developmental disorders, genetic defects, severe malnutrition, etc. 9. with severe liver diseases, severe kidney diseases defined as egfr less than 60, uncontrollable hypertension (systolic blood pressure >150 mmhg, diastolic blood pressure > 90 mmhg), diabetic complications, malignant tumors, various acute diseases, or acute attack period of chronic diseases. 10. has been diagnosed with congenital or acquired immune deficiency, hiv infection, lymphoma, leukemia or other autoimmune diseases. 11. with known or suspected diseases include acute respiratory diseases (e.g. influenza like illness, acute cough, sore throat), severe cardiovascular diseases, liver and kidney diseases, and malignant tumors. 12. has a history of coagulation dysfunction (e.g. coagulation factor deficiency, coagulation disease). 13. receiving anti-tb therapy. 14. patients receiving immunotherapy or inhibitor therapy within 3 months (continuous oral or infusion for more than 14 days). 15. live attenuated vaccine is inoculated within 1 month before this vaccination, other vaccines are inoculated within 14 days before this vaccination. 16. received blood products within 3 months before this vaccination 17. received other research drugs within 6 months before this vaccination. 18. other circumstances judged by investigators that are not suitable for this clinical trial.