inclusion criteria: * patients admitted to the issemym toluca medical center "arturo montiel rojas ", diagnosed with covid-19 confirmed by pcr. * patients in need of supplemental o2 with nasal prongs or reservoir-mask for sato2 \<90% and respiratory distress. * with concomitant diseases such as cardiovascular disease, diabetes mellitus 2, hypertension, overweight or obesity bmi \<35. * both sexes. * over 30 years old. * the patient tolerate oral feeding. * signing of the letter of informed consent.

inclusion criteria: * patients admitted to the issemym toluca medical center "arturo montiel rojas ", diagnosed with covid-19 confirmed by pcr. * patients in need of supplemental o2 with nasal prongs or reservoir-mask for sato2 \<90% and respiratory distress. * with concomitant diseases such as cardiovascular disease, diabetes mellitus 2, hypertension, overweight or obesity bmi \<35. * both sexes. * over 30 years old. * the patient tolerate oral feeding. * signing of the letter of informed consent.

inclusion criteria: - patients admitted to the issemym toluca medical center "arturo montiel rojas ", diagnosed with covid-19 confirmed by pcr. - patients in need of supplemental o2 with nasal prongs or reservoir-mask for sato2 <90% and respiratory distress. - with concomitant diseases such as cardiovascular disease, diabetes mellitus 2, hypertension, overweight or obesity bmi <35. - both sexes. - over 30 years old. - the patient tolerate oral feeding. - signing of the letter of informed consent.

inclusion criteria: - patients admitted to the issemym toluca medical center "arturo montiel rojas ", diagnosed with covid-19 confirmed by pcr. - patients in need of supplemental o2 with nasal prongs or reservoir-mask for sato2 <90% and respiratory distress. - with concomitant diseases such as cardiovascular disease, diabetes mellitus 2, hypertension, overweight or obesity bmi <35. - both sexes. - over 30 years old. - the patient tolerate oral feeding. - signing of the letter of informed consent.