inclusion criteria: 1. age \>18 years. 2. documented evidence of covid-19 and symptom onset of 7 days or less 3. acute hypoxia which will be defined as either low resting saturations \<94% or supplementary oxygen to maintain oxygen saturations at \>94%

inclusion criteria: 1. age \>18 years. 2. documented evidence of covid-19 and symptom onset of 7 days or less 3. acute hypoxia which will be defined as either low resting saturations \<94% or supplementary oxygen to maintain oxygen saturations at \>94%

inclusion criteria: age >18 years. documented evidence of covid-19 and symptom onset of 7 days or less acute hypoxia which will be defined as either low resting saturations <94% or supplementary oxygen to maintain oxygen saturations at >94%

inclusion criteria: age >18 years. documented evidence of covid-19 and symptom onset of 7 days or less acute hypoxia which will be defined as either low resting saturations <94% or supplementary oxygen to maintain oxygen saturations at >94%