inclusion criteria: * is within 72 hours from onset of symptoms consistent with covid 19 at time of study enrollment * has at least 2 of the following: fever (oral temperature ≥38°c), cough, shortness of breath, chest x ray changes consistent with covid-19 at time of screening * has peripheral capillary oxygen saturation (spo2) ≥94 by pulse oximetry at time of screening * has either a laboratory-confirmed sars-cov-2 infection as determined by fda-approved rapid diagnostic (e.g., pcr) assay * has a score of ≤ 2 on the 8-category niaid ordinal scale at time of screening * agrees to the collection of blood and urine samples, nasopharyngeal (np) swabs, and non-invasive oxygen monitoring (via pulse oximeter) per protocol * patient (or their legally authorized representative) is willing and able to provide written informed consent prior to performing study procedures * understands and agrees to comply with planned study procedures * women of childbearing potential must agree to either abstinence or use at least 1 primary form of contraception not including hormonal contraception from the time of screening through day 29 following randomization. all subjects of childbearing potential, including males with partners of childbearing potential, must use highly effective methods of birth control defined as those, alone or in combination, that result in a low failure rate (i.e., less than 1 percent per year) when used consistently and correctly. abstinence is not an acceptable method of contraception unless it is the subject's normal practice.

inclusion criteria: * is within 72 hours from onset of symptoms consistent with covid 19 at time of study enrollment * has at least 2 of the following: fever (oral temperature ≥38°c), cough, shortness of breath, chest x ray changes consistent with covid-19 at time of screening * has peripheral capillary oxygen saturation (spo2) ≥94 by pulse oximetry at time of screening * has either a laboratory-confirmed sars-cov-2 infection as determined by fda-approved rapid diagnostic (e.g., pcr) assay * has a score of ≤ 2 on the 8-category niaid ordinal scale at time of screening * agrees to the collection of blood and urine samples, nasopharyngeal (np) swabs, and non-invasive oxygen monitoring (via pulse oximeter) per protocol * patient (or their legally authorized representative) is willing and able to provide written informed consent prior to performing study procedures * understands and agrees to comply with planned study procedures * women of childbearing potential must agree to either abstinence or use at least 1 primary form of contraception not including hormonal contraception from the time of screening through day 29 following randomization. all subjects of childbearing potential, including males with partners of childbearing potential, must use highly effective methods of birth control defined as those, alone or in combination, that result in a low failure rate (i.e., less than 1 percent per year) when used consistently and correctly. abstinence is not an acceptable method of contraception unless it is the subject's normal practice.

inclusion criteria: - is within 72 hours from onset of symptoms consistent with covid 19 at time of study enrollment - has at least 2 of the following: fever (oral temperature ≥38°c), cough, shortness of breath, chest x ray changes consistent with covid-19 at time of screening - has peripheral capillary oxygen saturation (spo2) ≥94 by pulse oximetry at time of screening - has either a laboratory-confirmed sars-cov-2 infection as determined by fda-approved rapid diagnostic (e.g., pcr) assay - has a score of ≤ 2 on the 8-category niaid ordinal scale at time of screening - agrees to the collection of blood and urine samples, nasopharyngeal (np) swabs, and non-invasive oxygen monitoring (via pulse oximeter) per protocol - patient (or their legally authorized representative) is willing and able to provide written informed consent prior to performing study procedures - understands and agrees to comply with planned study procedures - women of childbearing potential must agree to either abstinence or use at least 1 primary form of contraception not including hormonal contraception from the time of screening through day 29 following randomization. all subjects of childbearing potential, including males with partners of childbearing potential, must use highly effective methods of birth control defined as those, alone or in combination, that result in a low failure rate (i.e., less than 1 percent per year) when used consistently and correctly. abstinence is not an acceptable method of contraception unless it is the subject's normal practice.

inclusion criteria: - is within 72 hours from onset of symptoms consistent with covid 19 at time of study enrollment - has at least 2 of the following: fever (oral temperature ≥38°c), cough, shortness of breath, chest x ray changes consistent with covid-19 at time of screening - has peripheral capillary oxygen saturation (spo2) ≥94 by pulse oximetry at time of screening - has either a laboratory-confirmed sars-cov-2 infection as determined by fda-approved rapid diagnostic (e.g., pcr) assay - has a score of ≤ 2 on the 8-category niaid ordinal scale at time of screening - agrees to the collection of blood and urine samples, nasopharyngeal (np) swabs, and non-invasive oxygen monitoring (via pulse oximeter) per protocol - patient (or their legally authorized representative) is willing and able to provide written informed consent prior to performing study procedures - understands and agrees to comply with planned study procedures - women of childbearing potential must agree to either abstinence or use at least 1 primary form of contraception not including hormonal contraception from the time of screening through day 29 following randomization. all subjects of childbearing potential, including males with partners of childbearing potential, must use highly effective methods of birth control defined as those, alone or in combination, that result in a low failure rate (i.e., less than 1 percent per year) when used consistently and correctly. abstinence is not an acceptable method of contraception unless it is the subject's normal practice.