inclusion criteria: 1. age at the time of the first dose of vaccine: aged 18 to 59 years (including boundary values) in the adult group, \>=60 years old in the older group, regardless of gender; 2. axillary body temperature is less than 37.3 ℃ on the day of enrollment; 3. based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; 4. subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.

inclusion criteria: 1. age at the time of the first dose of vaccine: aged 18 to 59 years (including boundary values) in the adult group, \>=60 years old in the older group, regardless of gender; 2. axillary body temperature is less than 37.3 ℃ on the day of enrollment; 3. based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; 4. subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: aged 18 to 59 years (including boundary values) in the adult group, >=60 years old in the older group, regardless of gender; axillary body temperature is less than 37.3 ℃ on the day of enrollment; based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.

inclusion criteria: age at the time of the first dose of vaccine: aged 18 to 59 years (including boundary values) in the adult group, >=60 years old in the older group, regardless of gender; axillary body temperature is less than 37.3 ℃ on the day of enrollment; based on the medical history and relevant physical examination and laboratory examination results, the investigator clinically determined that the patient was in good health; subjects have independent judgment ability, can read, understand and complete vaccination diary cards, and they participate voluntarily and sign an informed consent form.