Exclusion Criteria for Phase II: 1.Subject with a recent history of COVID-19 infection within 3 months of Screening.2.Subjects received an investigational vaccine or vaccine which have been granted an emergency use to prevent COVID-19 infection.3.Protocol defined laboratory assessments outside the range/limit defined in Appendix 2. Any other laboratory value if â?¥ Grade 2 as per DAIDs* criteria* Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events, corrected version 2.1, July 2017, of the US National Institutes of Health4.History of contact with a confirmed active SARS-CoV-2 positive patient within 14 days5.Any significant illness or any other current or pre-existing health condition (e.g., any major pulmonary, cardiovascular, renal, neurological, metabolic, gastro-intestinal, hepato biliary, haematological functional abnormality, mental or physical disability, blood dyscrasia, major congenital defects, etc.) which in the opinion of the Investigator may affect the safety of the subject or the study endpoints.6.History of allergic/hypersensitivity reactions or anaphylaxis to any vaccine or components of study vaccine.7.Subject has any acute illness (moderate or severe) at the time of vaccination and/or fever (oral temperature â?¥ 38°C or â?¥ 100.4 °F or its equivalent for axillary and tympanic) within 48 hours prior to vaccination.8.History of cancer, organ transplant, any other clinically significant immunosuppressive condition or autoimmune disease.9.Subjects willing to get married and planning for pregnancy within 4 months of study participation (only applicable for participants of 15 - (smaller than)18 years age).10.Prior major surgery or any radiation therapy within 4 weeks of Screening visit.11.Positive serologic test for HIV 1 and 2, HBsAg and HCV. 12.Current (within 14 days prior to Screening visit) or anticipated concomitant immune modifying or immunosuppressive therapy (excluding inhaled, topical skin or eye drop-containing corticosteroids, low-dose methotrexate, or corticosteroids at a dose less than 20 mg/day).13.Planned or actual receipt of any vaccine other than the study intervention within 30 days before and after each study vaccination.14.Eczema or other significant skin lesion or infection at the site of vaccination. 15.Administration of blood, blood products and/or plasma derivatives or any immunoglobulin preparation 90 days prior to screening visit. 16.Bleeding diathesis or condition associated with prolonged bleeding.17.Participating in another clinical trial within 30 days prior to Screening visit or planning to participate in another clinical trial during the study duration or planning to migrate.18.Any other condition which in the opinion of the Investigator may affect subjectâ??s safety or participation.Exclusion Criteria for Phase III: 1.Subject with a recent history of COVID-19 infection within 3 months from Screening2.Subjects received an investigational vaccine or vaccine which have been granted an emergency use to prevent COVID-19 infection.3.Any significant illness or any other current or pre-existing health condition (e.g. any major pulmonary, cardiovascular, renal, neurological, metabolic, gastro-intestinal, hepato biliary, haematological functional abnormality, mental or physical disability, blood dyscrasia, major congenital defects, etc.) which in the opinion of the Investigator may affect the safety of the subject or the study endpoints

Exclusion Criteria for Phase II: 1.Subject with a recent history of COVID-19 infection within 3 months of Screening.2.Subjects received an investigational vaccine or vaccine which have been granted an emergency use to prevent COVID-19 infection.3.Protocol defined laboratory assessments outside the range/limit defined in Appendix 2. Any other laboratory value if â?¥ Grade 2 as per DAIDs* criteria* Division of AIDS (DAIDS) Table for Grading the Severity of Adult and Pediatric Adverse Events, corrected version 2.1, July 2017, of the US National Institutes of Health4.History of contact with a confirmed active SARS-CoV-2 positive patient within 14 days5.Any significant illness or any other current or pre-existing health condition (e.g., any major pulmonary, cardiovascular, renal, neurological, metabolic, gastro-intestinal, hepato biliary, haematological functional abnormality, mental or physical disability, blood dyscrasia, major congenital defects, etc.) which in the opinion of the Investigator may affect the safety of the subject or the study endpoints.6.History of allergic/hypersensitivity reactions or anaphylaxis to any vaccine or components of study vaccine.7.Subject has any acute illness (moderate or severe) at the time of vaccination and/or fever (oral temperature â?¥ 38°C or â?¥ 100.4 °F or its equivalent for axillary and tympanic) within 48 hours prior to vaccination.8.History of cancer, organ transplant, any other clinically significant immunosuppressive condition or autoimmune disease.9.Subjects willing to get married and planning for pregnancy within 4 months of study participation (only applicable for participants of 15 - (smaller than)18 years age).10.Prior major surgery or any radiation therapy within 4 weeks of Screening visit.11.Positive serologic test for HIV 1 and 2, HBsAg and HCV. 12.Current (within 14 days prior to Screening visit) or anticipated concomitant immune modifying or immunosuppressive therapy (excluding inhaled, topical skin or eye drop-containing corticosteroids, low-dose methotrexate, or corticosteroids at a dose less than 20 mg/day).13.Planned or actual receipt of any vaccine other than the study intervention within 30 days before and after each study vaccination.14.Eczema or other significant skin lesion or infection at the site of vaccination. 15.Administration of blood, blood products and/or plasma derivatives or any immunoglobulin preparation 90 days prior to screening visit. 16.Bleeding diathesis or condition associated with prolonged bleeding.17.Participating in another clinical trial within 30 days prior to Screening visit or planning to participate in another clinical trial during the study duration or planning to migrate.18.Any other condition which in the opinion of the Investigator may affect subjectâ??s safety or participation.Exclusion Criteria for Phase III: 1.Subject with a recent history of COVID-19 infection within 3 months from Screening2.Subjects received an investigational vaccine or vaccine which have been granted an emergency use to prevent COVID-19 infection.3.Any significant illness or any other current or pre-existing health condition (e.g. any major pulmonary, cardiovascular, renal, neurological, metabolic, gastro-intestinal, hepato biliary, haematological functional abnormality, mental or physical disability, blood dyscrasia, major congenital defects, etc.) which in the opinion of the Investigator may affect the safety of the subject or the study endpoints