1. Age equal or more than 20 years 2. Body weigh equal or more than 40 kilograms 3. SARS-CoV-2 detected from nasopharyngeal specimen by antigen test kit and confirmed with SARS-CoV-2 PCR 4. Symptomatic equal or less than 7 days after onset of a symptom: At least one of the following symptom, fever, cough, runny nose, sore throat, dyspnea, chest discomfort, diarrhea 5. Absence or presence &lt,50%of pneumonia from chest X-ray or presence of pneumonia from chest CT with overall CT severity score 1-14 (mild to moderate pneumonia) 6. WHO clinical progression scale &lt, /= 3 7. Thai language communicable 8. Accept to follow up according to outpatient treatment or home isolation protocol 9. At least one of the following risk factor to deteriorate to severe illness: age more than 60 years, obesity or BMI &gt,/= 30 kg/ m2, diabetes mellitus, chronic kidney disease, heart disease and cardiovascular disease, COPD/ asthma, hypertension, liver disease with child pugh score A-B, receiving immunosuppressive therapy, cerebrovascular accident/stroke, intellectual disabilities, cancer with life expectancy more than 3 months, patients who disabilities and need medical intervention include tracheostomy, gastrostomy 10. Accept the informed consent

1. Age equal or more than 20 years 2. Body weigh equal or more than 40 kilograms 3. SARS-CoV-2 detected from nasopharyngeal specimen by antigen test kit and confirmed with SARS-CoV-2 PCR 4. Symptomatic equal or less than 7 days after onset of a symptom: At least one of the following symptom, fever, cough, runny nose, sore throat, dyspnea, chest discomfort, diarrhea 5. Absence or presence &lt,50%of pneumonia from chest X-ray or presence of pneumonia from chest CT with overall CT severity score 1-14 (mild to moderate pneumonia) 6. WHO clinical progression scale &lt, /= 3 7. Thai language communicable 8. Accept to follow up according to outpatient treatment or home isolation protocol 9. At least one of the following risk factor to deteriorate to severe illness: age more than 60 years, obesity or BMI &gt,/= 30 kg/ m2, diabetes mellitus, chronic kidney disease, heart disease and cardiovascular disease, COPD/ asthma, hypertension, liver disease with child pugh score A-B, receiving immunosuppressive therapy, cerebrovascular accident/stroke, intellectual disabilities, cancer with life expectancy more than 3 months, patients who disabilities and need medical intervention include tracheostomy, gastrostomy 10. Accept the informed consent