Created at Source Raw Value Validated value
April 8, 2022, 3:30 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention - Awake prone positioning.The intervention consists of self- or assisted positioning in the decubitus recumbent prone position (bed header at 0 grades) for as much as possible; with the possibility to alternate between complete prone position for 30 min to 2 hours; followed by lateral prone position for 30 min to 2 hours; followed by supine position (bed header 30-60 grades); followed by lateral prone position for 30 min to 2 hours; ending the cycle with 30 min to 2 hours in the prone position. These cycles are intended to increase patient comfort and can be repeated as many times as possible. Time in every position will be quantified.The intervention will be performed until the patient achieves a SpO2/FiO2 index greater than or equal to 235 with an oxygen device providing inspired oxygen fraction (FiO2) lower than 40%; for 12 continuous hours. If this happens; it will be considered as therapeutic success and the patient will be asked to interrupt prone positioning. If the patient does not meet these criteria during the 28-day follow-up; it will be considered as treatment failure. If the patient undergoes orotracheal intubation and invasive mechanical ventilation; it will also be considered as treatment failure and prone positioning will be performed unless the patient has contraindications hemodynamic instability.Control - Supine recumbent position.Patients in the control group will be encouraged to remain in the decubitus recumbent supine position (bed header 30-60 grades) for as much as possible. Patients will be able to freely choose any other position. The number of hours spent in all positions will be quantified; including lateral and complete prone positions. Patients in the control group will not be advised to follow the positioning cycle descri", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 1751, "treatment_name": "Awake prone position", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 1247, "treatment_name": "Supine position", "treatment_type": "Respiratory support", "pharmacological_treatment": "Non pharmacological treatment"}]