1. Pregnant women, nursing women or women of childbearing potential who are not actively avoiding pregnancy during the study. <br/ >2. Subjects with known current or chronic history of any of the following conditions, likely to affect participation in the study: any bleeding disorder <br/ >3. Subjects requiring chronic administration (defined as more than 14 days in total) of immunosuppressant (e.g., corticosteroids, cytotoxic drugs or antimetabolites, etc.) or other immune-modifying drugs (e.g., interferons). <br/ >4. Any confirmed or suspected immunosuppressive or immunodeficient condition, based on medical history and physical examination (no laboratory testing required). <br/ >5. Any medical condition that in the judgment of the investigator would make study participation unsafe. <br/ >

1. Pregnant women, nursing women or women of childbearing potential who are not actively avoiding pregnancy during the study. <br/ >2. Subjects with known current or chronic history of any of the following conditions, likely to affect participation in the study: any bleeding disorder <br/ >3. Subjects requiring chronic administration (defined as more than 14 days in total) of immunosuppressant (e.g., corticosteroids, cytotoxic drugs or antimetabolites, etc.) or other immune-modifying drugs (e.g., interferons). <br/ >4. Any confirmed or suspected immunosuppressive or immunodeficient condition, based on medical history and physical examination (no laboratory testing required). <br/ >5. Any medical condition that in the judgment of the investigator would make study participation unsafe. <br/ >