1.18 years old and above, able to provide legal proof of identity, 2.Participants voluntarily agreed to participate in the study and signed an informed consent form, 3.The subject has the ability to understand the research process and is willing and able to comply with all research proposals and other requirements of the study, 4.Body temperature <= 37.3 degree C (armpit body temperature) on the day of enrollment, 5.SARS-CoV-2 is negative in throat swabs by RT-PCR and there is no history of SARS, SARS-CoV-2 or MERS infection, 6.(Consults) Non-pregnant period (negative result of pregnancy test), non-lactation period, 7.(Consults) The female subjects of childbearing age had taken effective contraceptive measures one month before they are enrolled in the study group, 8.(Consults) Women and men of child-bearing age agree to use effective contraception from screening period until 12 months after vaccination, 9.(Consults) Female and male participants of child-bearing age agree that do not donate eggs (eggs, oocytes) for assisted reproduction (female subjects of reproductive age) or avoid sperm donation (male subjects) from screening period until 12 months after vaccination.

1.18 years old and above, able to provide legal proof of identity, 2.Participants voluntarily agreed to participate in the study and signed an informed consent form, 3.The subject has the ability to understand the research process and is willing and able to comply with all research proposals and other requirements of the study, 4.Body temperature <= 37.3 degree C (armpit body temperature) on the day of enrollment, 5.SARS-CoV-2 is negative in throat swabs by RT-PCR and there is no history of SARS, SARS-CoV-2 or MERS infection, 6.(Consults) Non-pregnant period (negative result of pregnancy test), non-lactation period, 7.(Consults) The female subjects of childbearing age had taken effective contraceptive measures one month before they are enrolled in the study group, 8.(Consults) Women and men of child-bearing age agree to use effective contraception from screening period until 12 months after vaccination, 9.(Consults) Female and male participants of child-bearing age agree that do not donate eggs (eggs, oocytes) for assisted reproduction (female subjects of reproductive age) or avoid sperm donation (male subjects) from screening period until 12 months after vaccination.