* patient who had allergy or contraindication to hcq, pregnant and lactating females, and patients with immune diseases, cardiac problem, had history of acute kidney injury or who received multiple cycles of anticoagulants were excluded from the study. written informed consent was obtained from each participant. all study risks and benefits were thoroughly explained to patients' prior participation

* patient who had allergy or contraindication to hcq, pregnant and lactating females, and patients with immune diseases, cardiac problem, had history of acute kidney injury or who received multiple cycles of anticoagulants were excluded from the study. written informed consent was obtained from each participant. all study risks and benefits were thoroughly explained to patients' prior participation

patient who had allergy or contraindication to hcq, pregnant and lactating females, and patients with immune diseases, cardiac problem, had history of acute kidney injury or who received multiple cycles of anticoagulants were excluded from the study. written informed consent was obtained from each participant. all study risks and benefits were thoroughly explained to patients' prior participation

patient who had allergy or contraindication to hcq, pregnant and lactating females, and patients with immune diseases, cardiac problem, had history of acute kidney injury or who received multiple cycles of anticoagulants were excluded from the study. written informed consent was obtained from each participant. all study risks and benefits were thoroughly explained to patients' prior participation