1. if female, pregnant or breastfeeding, or planning a pregnancy during the study. 2. moderate covid-19, as defined per nih: a. moderate covid-19: individuals who have evidence of lower respiratory disease by clinical assessment or imaging and a saturation of oxygen (spo2) ≥94% on room air at sea level. 3. severe or critical covid-19, as defined per nih: 1. severe covid-19: respiratory frequency \>30 breaths per minute, spo2 \<94% on room air at sea level, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (pao2/fio2) \<300 mmhg, or lung infiltrates \>50%. 2. critical covid-19: respiratory failure, septic shock, and/or multiple organ dysfunction. 4. history of previous confirmed sars-cov-2 infection. 5. history of significantly abnormal liver function (child pugh c). 6. history of chronic kidney disease (ckd) ≥ stage 4 or need of dialysis treatment. 7. any pre-existing condition that increases risk of thrombosis. 8. history of allergic reactions to ivermectin, fluoxetine, prednisolone, or vitamins c, albendazole, any of its excipients. 9. concomitant use of medications that are highly dependent of cyp 2d6 for clearance and for which elevated plasma concentrations may be associated with serious and/or life-threatening events. 1. phenytoin 2. tricyclic antidepressants 3. antipsychotics: phenothiazines (i.e., chlorpromazine) haloperidol and most atypical (i.e., amitriptyline, aripiprazole, brexpiprazole, risperidone). 4. donepezil 5. tamoxifen 6. antiarrhytmics: propafenone, flecainide 7. amphetamine 10. concomitant use of ssris, snris, or tricyclic antidepressants, linezolid, or methylene blue (rationale: increased risk of serotonin syndrome or tca overdose). 11. concomitant use of drugs that could prolong the qt interval: 1. specific antipsychotics: ziprasidone, iloperidone, chlorpromazine, mesoridazine, droperidol 2. specific antibiotics: erythromycin, gatifloxacin, moxifloxacin, sparfloxacin 3. class 1a antiarrhytmics: amiodarone, sotalol 12. concomitant use of donepezil (s1r agonist) or sertraline (s1r antagonist) 13. uncontrolled psychiatric disorders, or suicidal ideation. 14. inability to consent and/or comply with study protocol, in the opinion of the investigator.

1. if female, pregnant or breastfeeding, or planning a pregnancy during the study. 2. moderate covid-19, as defined per nih: a. moderate covid-19: individuals who have evidence of lower respiratory disease by clinical assessment or imaging and a saturation of oxygen (spo2) ≥94% on room air at sea level. 3. severe or critical covid-19, as defined per nih: 1. severe covid-19: respiratory frequency \>30 breaths per minute, spo2 \<94% on room air at sea level, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (pao2/fio2) \<300 mmhg, or lung infiltrates \>50%. 2. critical covid-19: respiratory failure, septic shock, and/or multiple organ dysfunction. 4. history of previous confirmed sars-cov-2 infection. 5. history of significantly abnormal liver function (child pugh c). 6. history of chronic kidney disease (ckd) ≥ stage 4 or need of dialysis treatment. 7. any pre-existing condition that increases risk of thrombosis. 8. history of allergic reactions to ivermectin, fluoxetine, prednisolone, or vitamins c, albendazole, any of its excipients. 9. concomitant use of medications that are highly dependent of cyp 2d6 for clearance and for which elevated plasma concentrations may be associated with serious and/or life-threatening events. 1. phenytoin 2. tricyclic antidepressants 3. antipsychotics: phenothiazines (i.e., chlorpromazine) haloperidol and most atypical (i.e., amitriptyline, aripiprazole, brexpiprazole, risperidone). 4. donepezil 5. tamoxifen 6. antiarrhytmics: propafenone, flecainide 7. amphetamine 10. concomitant use of ssris, snris, or tricyclic antidepressants, linezolid, or methylene blue (rationale: increased risk of serotonin syndrome or tca overdose). 11. concomitant use of drugs that could prolong the qt interval: 1. specific antipsychotics: ziprasidone, iloperidone, chlorpromazine, mesoridazine, droperidol 2. specific antibiotics: erythromycin, gatifloxacin, moxifloxacin, sparfloxacin 3. class 1a antiarrhytmics: amiodarone, sotalol 12. concomitant use of donepezil (s1r agonist) or sertraline (s1r antagonist) 13. uncontrolled psychiatric disorders, or suicidal ideation. 14. inability to consent and/or comply with study protocol, in the opinion of the investigator.

if female, pregnant or breastfeeding, or planning a pregnancy during the study. moderate covid-19, as defined per nih: a. moderate covid-19: individuals who have evidence of lower respiratory disease by clinical assessment or imaging and a saturation of oxygen (spo2) ≥94% on room air at sea level. severe or critical covid-19, as defined per nih: severe covid-19: respiratory frequency >30 breaths per minute, spo2 <94% on room air at sea level, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (pao2/fio2) <300 mmhg, or lung infiltrates >50%. critical covid-19: respiratory failure, septic shock, and/or multiple organ dysfunction. history of previous confirmed sars-cov-2 infection. history of significantly abnormal liver function (child pugh c). history of chronic kidney disease (ckd) ≥ stage 4 or need of dialysis treatment. any pre-existing condition that increases risk of thrombosis. history of allergic reactions to ivermectin, fluoxetine, prednisolone, or vitamins c, albendazole, any of its excipients. concomitant use of medications that are highly dependent of cyp 2d6 for clearance and for which elevated plasma concentrations may be associated with serious and/or life-threatening events. phenytoin tricyclic antidepressants antipsychotics: phenothiazines (i.e., chlorpromazine) haloperidol and most atypical (i.e., amitriptyline, aripiprazole, brexpiprazole, risperidone). donepezil tamoxifen antiarrhytmics: propafenone, flecainide amphetamine concomitant use of ssris, snris, or tricyclic antidepressants, linezolid, or methylene blue (rationale: increased risk of serotonin syndrome or tca overdose). concomitant use of drugs that could prolong the qt interval: specific antipsychotics: ziprasidone, iloperidone, chlorpromazine, mesoridazine, droperidol specific antibiotics: erythromycin, gatifloxacin, moxifloxacin, sparfloxacin class 1a antiarrhytmics: amiodarone, sotalol concomitant use of donepezil (s1r agonist) or sertraline (s1r antagonist) uncontrolled psychiatric disorders, or suicidal ideation. inability to consent and/or comply with study protocol, in the opinion of the investigator.

if female, pregnant or breastfeeding, or planning a pregnancy during the study. moderate covid-19, as defined per nih: a. moderate covid-19: individuals who have evidence of lower respiratory disease by clinical assessment or imaging and a saturation of oxygen (spo2) ≥94% on room air at sea level. severe or critical covid-19, as defined per nih: severe covid-19: respiratory frequency >30 breaths per minute, spo2 <94% on room air at sea level, ratio of arterial partial pressure of oxygen to fraction of inspired oxygen (pao2/fio2) <300 mmhg, or lung infiltrates >50%. critical covid-19: respiratory failure, septic shock, and/or multiple organ dysfunction. history of previous confirmed sars-cov-2 infection. history of significantly abnormal liver function (child pugh c). history of chronic kidney disease (ckd) ≥ stage 4 or need of dialysis treatment. any pre-existing condition that increases risk of thrombosis. history of allergic reactions to ivermectin, fluoxetine, prednisolone, or vitamins c, albendazole, any of its excipients. concomitant use of medications that are highly dependent of cyp 2d6 for clearance and for which elevated plasma concentrations may be associated with serious and/or life-threatening events. phenytoin tricyclic antidepressants antipsychotics: phenothiazines (i.e., chlorpromazine) haloperidol and most atypical (i.e., amitriptyline, aripiprazole, brexpiprazole, risperidone). donepezil tamoxifen antiarrhytmics: propafenone, flecainide amphetamine concomitant use of ssris, snris, or tricyclic antidepressants, linezolid, or methylene blue (rationale: increased risk of serotonin syndrome or tca overdose). concomitant use of drugs that could prolong the qt interval: specific antipsychotics: ziprasidone, iloperidone, chlorpromazine, mesoridazine, droperidol specific antibiotics: erythromycin, gatifloxacin, moxifloxacin, sparfloxacin class 1a antiarrhytmics: amiodarone, sotalol concomitant use of donepezil (s1r agonist) or sertraline (s1r antagonist) uncontrolled psychiatric disorders, or suicidal ideation. inability to consent and/or comply with study protocol, in the opinion of the investigator.