* recent use of illicit drugs or alcohol abuse * known allergy to tradipitant or other neurokinin-1 antagonists * pregnancy * known hiv, hbv, or hcv infection * malignant tumor, other serious systemic diseases * inability to provide informed consent or to have an authorized relative or designated person provide informed consent, or to comply with the protocol requirements

* recent use of illicit drugs or alcohol abuse * known allergy to tradipitant or other neurokinin-1 antagonists * pregnancy * known hiv, hbv, or hcv infection * malignant tumor, other serious systemic diseases * inability to provide informed consent or to have an authorized relative or designated person provide informed consent, or to comply with the protocol requirements

- recent use of illicit drugs or alcohol abuse - known allergy to tradipitant or other neurokinin-1 antagonists - pregnancy - known hiv, hbv, or hcv infection - malignant tumor, other serious systemic diseases - inability to provide informed consent or to have an authorized relative or designated person provide informed consent, or to comply with the protocol requirements

- recent use of illicit drugs or alcohol abuse - known allergy to tradipitant or other neurokinin-1 antagonists - pregnancy - known hiv, hbv, or hcv infection - malignant tumor, other serious systemic diseases - inability to provide informed consent or to have an authorized relative or designated person provide informed consent, or to comply with the protocol requirements