inclusion criteria: * subject must be 18 to 49 years of age inclusive; * body weight ≤100 kg and body mass index (bmi) within the range of 19.0-24.0kg/m2 (inclusive); * male or female;

inclusion criteria: * subject must be 18 to 49 years of age inclusive; * body weight ≤100 kg and body mass index (bmi) within the range of 19.0-24.0kg/m2 (inclusive); * male or female;

inclusion criteria: - subject must be 18 to 49 years of age inclusive; - body weight ≤100 kg and body mass index (bmi) within the range of 19.0-24.0kg/m2 (inclusive); - male or female;

inclusion criteria: - subject must be 18 to 49 years of age inclusive; - body weight ≤100 kg and body mass index (bmi) within the range of 19.0-24.0kg/m2 (inclusive); - male or female;