Created at Source Raw Value Validated value
June 25, 2024, noon usa

1. known pregnancy or nursing mothers 2. known allergy to statins or colchicine 3. patient is on chronic colchicine or oral corticosteroid treatment 4. acute liver disease defined by elevated transaminases (ast/alt \> 3x uln) 5. severe chronic kidney disease defined as glomerular filtration rate (gfr) \< 30ml/min1.73 m2 6. severe qtc prolongation (\>500ms narrow qrs\<120ms and \>550ms for wide qrs\>120) 7. presents with severe disease on admission (who ordinal scale of clinical improvement scores 5-8) 8. rhabdomyolysis or cpk \> 5x uln 9. thrombocytopenia defined as platelet count \< 50,000 / mm3 10. leukopenia defined as white blood cell count \< 3000 ml 11. severe anemia defined as hemoglobin value \<8 g/100ml 12. participation in any other clinical trial of an experimental treatment for covid-19

1. known pregnancy or nursing mothers 2. known allergy to statins or colchicine 3. patient is on chronic colchicine or oral corticosteroid treatment 4. acute liver disease defined by elevated transaminases (ast/alt \> 3x uln) 5. severe chronic kidney disease defined as glomerular filtration rate (gfr) \< 30ml/min1.73 m2 6. severe qtc prolongation (\>500ms narrow qrs\<120ms and \>550ms for wide qrs\>120) 7. presents with severe disease on admission (who ordinal scale of clinical improvement scores 5-8) 8. rhabdomyolysis or cpk \> 5x uln 9. thrombocytopenia defined as platelet count \< 50,000 / mm3 10. leukopenia defined as white blood cell count \< 3000 ml 11. severe anemia defined as hemoglobin value \<8 g/100ml 12. participation in any other clinical trial of an experimental treatment for covid-19

Nov. 16, 2021, 6:30 p.m. usa

known pregnancy or nursing mothers known allergy to statins or colchicine patient is on chronic colchicine or oral corticosteroid treatment acute liver disease defined by elevated transaminases (ast/alt > 3x uln) severe chronic kidney disease defined as glomerular filtration rate (gfr) < 30ml/min1.73 m2 severe qtc prolongation (>500ms narrow qrs<120ms and >550ms for wide qrs>120) presents with severe disease on admission (who ordinal scale of clinical improvement scores 5-8) rhabdomyolysis or cpk > 5x uln thrombocytopenia defined as platelet count < 50,000 / mm3 leukopenia defined as white blood cell count < 3000 ml severe anemia defined as hemoglobin value <8 g/100ml participation in any other clinical trial of an experimental treatment for covid-19

known pregnancy or nursing mothers known allergy to statins or colchicine patient is on chronic colchicine or oral corticosteroid treatment acute liver disease defined by elevated transaminases (ast/alt > 3x uln) severe chronic kidney disease defined as glomerular filtration rate (gfr) < 30ml/min1.73 m2 severe qtc prolongation (>500ms narrow qrs<120ms and >550ms for wide qrs>120) presents with severe disease on admission (who ordinal scale of clinical improvement scores 5-8) rhabdomyolysis or cpk > 5x uln thrombocytopenia defined as platelet count < 50,000 / mm3 leukopenia defined as white blood cell count < 3000 ml severe anemia defined as hemoglobin value <8 g/100ml participation in any other clinical trial of an experimental treatment for covid-19

Oct. 26, 2020, 11:31 p.m. usa

1. known pregnancy or nursing mothers 2. known allergy to statins or colchicine 3. patient is on chronic colchicine or oral corticosteroid treatment 4. acute liver disease defined by elevated transaminases (ast/alt > 3x uln) 5. severe chronic kidney disease defined as glomerular filtration rate (gfr) < 30ml/min1.73 m2 6. severe qtc prolongation (>500ms narrow qrs<120ms and >550ms for wide qrs>120) 7. presents with severe disease on admission (who ordinal scale of clinical improvement scores 5-8) 8. rhabdomyolysis or cpk > 5x uln 9. thrombocytopenia defined as platelet count < 50,000 / mm3 10. leukopenia defined as white blood cell count < 3000 ml 11. severe anemia defined as hemoglobin value <8 g/100ml 12. participation in any other clinical trial of an experimental treatment for covid-19

1. known pregnancy or nursing mothers 2. known allergy to statins or colchicine 3. patient is on chronic colchicine or oral corticosteroid treatment 4. acute liver disease defined by elevated transaminases (ast/alt > 3x uln) 5. severe chronic kidney disease defined as glomerular filtration rate (gfr) < 30ml/min1.73 m2 6. severe qtc prolongation (>500ms narrow qrs<120ms and >550ms for wide qrs>120) 7. presents with severe disease on admission (who ordinal scale of clinical improvement scores 5-8) 8. rhabdomyolysis or cpk > 5x uln 9. thrombocytopenia defined as platelet count < 50,000 / mm3 10. leukopenia defined as white blood cell count < 3000 ml 11. severe anemia defined as hemoglobin value <8 g/100ml 12. participation in any other clinical trial of an experimental treatment for covid-19