inclusion criteria: * age ≥ 18 years old * patient with laboratory-confirmed sars-cov-2 infection as determined by pcr \< 96 h (at initial diagnosis or persistent carriage \<96 h) * hospitalized patient with covid-19 requiring oxygen therapy and targeting in phase b : * patients under oxygen therapy such as nasal cannula/mask or non-invasive ventilation with pao2/fio2 \> 200 mmhg. * patients hospitalized for less than 7 days. * patients with symptoms for less than 10 days or rt-pcr (\<96h) with cycle treshold \< 25. * social security coverage * signed informed consent (by patient or their legally authorized representative)

inclusion criteria: * age ≥ 18 years old * patient with laboratory-confirmed sars-cov-2 infection as determined by pcr \< 96 h (at initial diagnosis or persistent carriage \<96 h) * hospitalized patient with covid-19 requiring oxygen therapy and targeting in phase b : * patients under oxygen therapy such as nasal cannula/mask or non-invasive ventilation with pao2/fio2 \> 200 mmhg. * patients hospitalized for less than 7 days. * patients with symptoms for less than 10 days or rt-pcr (\<96h) with cycle treshold \< 25. * social security coverage * signed informed consent (by patient or their legally authorized representative)

inclusion criteria: - age ≥ 18 years old - patient with laboratory-confirmed sars-cov-2 infection as determined by pcr < 96 h (at initial diagnosis or persistent carriage <96 h) - hospitalized patient with covid-19 requiring oxygen therapy and targeting in phase b : - patients under oxygen therapy such as nasal cannula/mask or non-invasive ventilation with pao2/fio2 > 200 mmhg. - patients hospitalized for less than 7 days. - patients with symptoms for less than 10 days or rt-pcr (<96h) with cycle treshold < 25. - social security coverage - signed informed consent (by patient or their legally authorized representative)

inclusion criteria: - age ≥ 18 years old - patient with laboratory-confirmed sars-cov-2 infection as determined by pcr < 96 h (at initial diagnosis or persistent carriage <96 h) - hospitalized patient with covid-19 requiring oxygen therapy and targeting in phase b : - patients under oxygen therapy such as nasal cannula/mask or non-invasive ventilation with pao2/fio2 > 200 mmhg. - patients hospitalized for less than 7 days. - patients with symptoms for less than 10 days or rt-pcr (<96h) with cycle treshold < 25. - social security coverage - signed informed consent (by patient or their legally authorized representative)

inclusion criteria: - age ≥ 18 years old - patient with laboratory-confirmed covid-19 infection as determined by pcr < 96 h (at initial diagnosis or aggravation phase with persistent carriage <96 h) - inpatients with covid-19 of any duration, requiring oxygen therapy (mask or mechanical ventilation). - social security coverage - signed informed consent (by patient or their legally authorized representative)

inclusion criteria: - age ≥ 18 years old - patient with laboratory-confirmed covid-19 infection as determined by pcr < 96 h (at initial diagnosis or aggravation phase with persistent carriage <96 h) - inpatients with covid-19 of any duration, requiring oxygen therapy (mask or mechanical ventilation). - social security coverage - signed informed consent (by patient or their legally authorized representative)