inclusion criteria: * age: 18 years or more. * patient with covid-19 confirmed with nuclear acid testing * critically ill patients with covid-19 on mechanical ventilation. potencially critically ill patients (with acute respiratory distress syndrome, septic shock and/or multiple organ failure) with covid-19. * diagnosed with acute respiratory distress syndrome. * informed consent.

inclusion criteria: * age: 18 years or more. * patient with covid-19 confirmed with nuclear acid testing * critically ill patients with covid-19 on mechanical ventilation. potencially critically ill patients (with acute respiratory distress syndrome, septic shock and/or multiple organ failure) with covid-19. * diagnosed with acute respiratory distress syndrome. * informed consent.

inclusion criteria: - age: 18 years or more. - patient with covid-19 confirmed with nuclear acid testing - critically ill patients with covid-19 on mechanical ventilation. potencially critically ill patients (with acute respiratory distress syndrome, septic shock and/or multiple organ failure) with covid-19. - diagnosed with acute respiratory distress syndrome. - informed consent.

inclusion criteria: - age: 18 years or more. - patient with covid-19 confirmed with nuclear acid testing - critically ill patients with covid-19 on mechanical ventilation. potencially critically ill patients (with acute respiratory distress syndrome, septic shock and/or multiple organ failure) with covid-19. - diagnosed with acute respiratory distress syndrome. - informed consent.