Created at Source Raw Value Validated value
May 15, 2022, 7:42 a.m. irct

[{"arm_notes": "", "treatment_id": null, "treatment_name": "TODO Treatment - DrugsAll consecutive adult patients who are candidates for Allo-HSCT at HORCSCT are recruited. They sign an informed consent to administer the Pastocovac vaccine and take blood samples. All patients who meet the inclusion criteria are enrolled to study from 3 to 12 months after Allo-HSCT and will be vaccinated with the first two doses of Pastucovac at a 4-week (\u00b17 days) interval and a third additional dose with an 8-week (\u00b17 days) interval from the second dose. Peripheral blood samples are collected before conditioning and before the first dose of vaccine to test particular lymphocyte subpopulations and SARS-CoV-2 IgG titers. The blood samples are also collected three weeks (\u00b1 one week) after each dose of vaccine to assess serologic response by SARS-CoV-2 IgG titer.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 2438, "treatment_name": "Pastocovac", "treatment_type": "Protein subunit", "pharmacological_treatment": "Vaccine"}]

Jan. 13, 2022, 11 a.m. irct

[{"arm_notes": "", "treatment_id": null, "treatment_name": "TODO Treatment - DrugsAll consecutive patients who are a candidate for ASCT and agree to receive post-transplant COVID-19 vaccines will be enrolled. From three months post-transplant in the absence of grade 3,4 acute GVHD, patients will receive an approved COVID-19 vaccine according to the EBMT guideline (version 7.0) and a second dose will receive after four weeks (\u00b17 days) interval. The serologic response will be assessed by measurement of SARS-CoV-2 specific IgG (anti-S1) before the first vaccine, one week before the second vaccine, four weeks after the second vaccine, and six months after the first vaccine.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "2,Days0-28;From 3 months post-transplant in the absence of grade 3,4 acute GVHD, patients will receive an approved COVID-19 vaccine according to the EBMT guideline (version 7.0) and a second dose will receive after four weeks (\u00b17 days) interval.", "treatment_id": 1911, "treatment_name": "Covid-19 vaccine", "treatment_type": "Other covid vaccine", "pharmacological_treatment": "Vaccine"}]