Existence of any obstetric problems such as premature rupture of the amniotic membrane, placental abruption History of receiving probiotic supplement for up to one week before enrollment Presence of underlying diseases and gastrointestinal disorders such as IBD Presence chronic diseases under treatment (such as asthma and allergies, heart failure) and acquired or congenital immunodeficiencies

Existence of any obstetric problems such as premature rupture of the amniotic membrane, placental abruption History of receiving probiotic supplement for up to one week before enrollment Presence of underlying diseases and gastrointestinal disorders such as IBD Presence chronic diseases under treatment (such as asthma and allergies, heart failure) and acquired or congenital immunodeficiencies