Patients in the acute phase with Laboratory confirmation of SARS-COV-2 infection with RT-PCR Pneumonia confirmed by chest x-ray or Computed tomography Scan Respiratory rate> 30 times/minute Oxygen Saturation less than 93% Arterial oxygen partial pressure (Pao2) /oxygen inhalation(Fio2) less than 300 mm Hg No history of tumor or malignant disease CRP greater than normal range

Patients in the acute phase with Laboratory confirmation of SARS-COV-2 infection with RT-PCR Pneumonia confirmed by chest x-ray or Computed tomography Scan Respiratory rate> 30 times/minute Oxygen Saturation less than 93% Arterial oxygen partial pressure (Pao2) /oxygen inhalation(Fio2) less than 300 mm Hg No history of tumor or malignant disease CRP greater than normal range