Pregnant patient with a positive pregnancy test or during lactation or who is planning to become pregnant during the study The definitive history of acquired or inherited immune deficiency diseases The definitive psychotic illness, A history of serious mental illness or a history of suicide. Any active or treated Cancerous diseases. Creatinine greater than 1.7 mg/dL Co-infection of human immunodeficiency viruses, Hepatitis B, Hepatitis C and Human T-lymphotropic virus Any cardiac hemodynamic disorder Positive PPD test Positive syphilis test Treatment with cytotoxic drugs one month prior study

Pregnant patient with a positive pregnancy test or during lactation or who is planning to become pregnant during the study The definitive history of acquired or inherited immune deficiency diseases The definitive psychotic illness, A history of serious mental illness or a history of suicide. Any active or treated Cancerous diseases. Creatinine greater than 1.7 mg/dL Co-infection of human immunodeficiency viruses, Hepatitis B, Hepatitis C and Human T-lymphotropic virus Any cardiac hemodynamic disorder Positive PPD test Positive syphilis test Treatment with cytotoxic drugs one month prior study