Created at Source Raw Value Validated value
Sept. 13, 2021, 12:30 p.m. irct

[{"arm_notes": "", "treatment_id": null, "treatment_name": "TODO Treatment - DevicesIntervention group includes 10 patients who enter the study after obtaining the informed consent of the patient or her companion and receive the standard COVID-19 treatment regimen along with 3 sessions of hemoperfusion according to the protocol provided by the Ministry of Health.The standard treatment includes the antiviral drug remedicivier and interferon ReciGen and the use of corticosteroids and dexamethasone and other complementary measures such as anticoagulants and antacids and sedatives.The use of a homeperfusion device can be alone or in combination. In the combined use of hemoperfusion, the cartridge is placed before the hemodialysis filter or hemofilter.Cartridge used: Jafron HA 330 - Number of sessions: 3 - Device: Hemoperfusion - Pump speed of the device: 250 to 300 - Duration of each session: 4 hours - Interval between sessions: 8 to 12 hours - Low-dose of heparin will be infused. It is prescribed at a dose of 10 to 15 units per kilogram per hour to avoid cartridge damage.If CVVH mode is established and added from CRRT, the dose of heparin will increase to 15-20 units per kilogram per hour.For hemoperfusion, you can use a special device for hemoperfusion or if you do not have access to a hemoperfusion device, you can use a hemodialysis machine, because to perform hemoperfusion, you need vascular access (shaldon) and a pump that removes blood from the body and returns it to the body And a hemodialysis machine makes this possible.Patients are monitored daily for vital signs, electrolytes, blood sugar, liver tests, kidney tests, blood cells, coagulation factors, LDH, inflammatory factors, and chest radiographs.To compare the effectiveness and speed of recovery between the two intervention and control groups, changes in clinical symptoms (fever, oxygen saturation, alertness, blood pressure, heart rate, respiratory distress, etc.) and paraclinical changes (changes in chest imaging, changes in lymphocyte count). LDH, changes in CRP, ESR, D.DIMER, serum creatinine, ALT, AST, bilirubin and alkaline phosphatase, interleukin 6 and ferritin) are checked twice a week.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "TODO N/AControl group includes 10 patients who enter the study after obtaining the informed consent of the patient or her companion and receive the standard COVID-19 treatment regimen.The standard treatment includes the antiviral drug remedicivier and interferon ReciGen and the use of corticosteroids and dexamethasone and other complementary measures such as anticoagulants and antacids and sedatives.Patients are monitored daily for vital signs, electrolytes, blood sugar, liver tests, kidney tests, blood cells, coagulation factors, LDH, inflammatory factors, and chest radiographs.To compare the effectiveness and speed of recovery between the two intervention and control groups, changes in clinical symptoms (fever, oxygen saturation, alertness, blood pressure, heart rate, respiratory distress, etc.) and paraclinical changes (changes in chest imaging, changes in lymphocyte count). LDH, changes in CRP, ESR, D.DIMER, serum creatinine, ALT, AST, bilirubin and alkaline phosphatase, interleukin 6 and ferritin) are checked twice a week.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 566, "treatment_name": "Hemoperfusion", "treatment_type": "Non-pharmocologic agent", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]