Age 18 to 70 years Body mass index between 18 and 35 kg per square meter No current or previous COVID-19 disease No pregnancy Using safe methods of contraception Signing the informed consent form Having Iranian citizenship Participants should be able to read and understand informed consent, preferably having an education at a diploma or higher level. Temperatures less than or equal to 37.2 ° C, sublingual, measured by a digital thermometer Negative IgG and IgM antibody titers against COVID-19 N antigen Negative RT-PCR -test for SARS-CoV-2 IgG ELISA negative blood test against HIV Heart rate between 60 and 100 Systolic blood pressure (between 90 and 140 mm Hg), Diastolic blood pressure (between 60 and 90 mm Hg) Committing to observing the requested behavioral protocol to reduce the risk of COVID-19 Negative pregnancy test for β-hCG on the day of screening and the day of vaccination Clinical trial participants should refrain from donating blood or plasma from the first vaccination until three months after the last vaccination. Participants should not enter any other trial while in this study Expressing readiness to remain in the study for the entire study period Use one of a safe methods of contraception in men and women up to 3 months after the last dose of the vaccine

Age 18 to 70 years Body mass index between 18 and 35 kg per square meter No current or previous COVID-19 disease No pregnancy Using safe methods of contraception Signing the informed consent form Having Iranian citizenship Participants should be able to read and understand informed consent, preferably having an education at a diploma or higher level. Temperatures less than or equal to 37.2 ° C, sublingual, measured by a digital thermometer Negative IgG and IgM antibody titers against COVID-19 N antigen Negative RT-PCR -test for SARS-CoV-2 IgG ELISA negative blood test against HIV Heart rate between 60 and 100 Systolic blood pressure (between 90 and 140 mm Hg), Diastolic blood pressure (between 60 and 90 mm Hg) Committing to observing the requested behavioral protocol to reduce the risk of COVID-19 Negative pregnancy test for β-hCG on the day of screening and the day of vaccination Clinical trial participants should refrain from donating blood or plasma from the first vaccination until three months after the last vaccination. Participants should not enter any other trial while in this study Expressing readiness to remain in the study for the entire study period Use one of a safe methods of contraception in men and women up to 3 months after the last dose of the vaccine

Age 18 to 70 years Body mass index between 18 and 35 kg per square meter No current or previous COVID-19 disease No pregnancy Using safe methods of contraception Signing the informed consent form Having Iranian citizenship Participants should be able to read and understand informed consent, preferably having education at diploma or higher level Temperatures less than or equal to 37.2 ° C sublingually measured by a digital thermometer Negative IgG and IgM antibody titers against COVID-19 N antigen Negative RT-PCR -test for SARS-CoV-2 IgG ELISA negative blood test against HIV Heart rate between 60 and 100 Systolic blood pressure (between 90 and 140 mm Hg), Diastolic blood pressure (between 60 and 90 mm Hg) Committing to observe requested behavioral protocol to reduce the risk of COVID-19 Negative pregnancy test for β-hCG on the day of screening and the day of vaccination Clinical trial participants should refrain from donating blood or plasma from the first vaccination until 3 months after the last vaccination. Participants should not enter any other trial while in this study Expressing a person's readiness to remain among the people monitored in the study for the entire study period until the research process is completed within 14 months Use one of a safe method of contraception in men and women up to 3 months after the last dose of the vaccine

Age 18 to 70 years Body mass index between 18 and 35 kg per square meter No current or previous COVID-19 disease No pregnancy Using safe methods of contraception Signing the informed consent form Having Iranian citizenship Participants should be able to read and understand informed consent, preferably having education at diploma or higher level Temperatures less than or equal to 37.2 ° C sublingually measured by a digital thermometer Negative IgG and IgM antibody titers against COVID-19 N antigen Negative RT-PCR -test for SARS-CoV-2 IgG ELISA negative blood test against HIV Heart rate between 60 and 100 Systolic blood pressure (between 90 and 140 mm Hg), Diastolic blood pressure (between 60 and 90 mm Hg) Committing to observe requested behavioral protocol to reduce the risk of COVID-19 Negative pregnancy test for β-hCG on the day of screening and the day of vaccination Clinical trial participants should refrain from donating blood or plasma from the first vaccination until 3 months after the last vaccination. Participants should not enter any other trial while in this study Expressing a person's readiness to remain among the people monitored in the study for the entire study period until the research process is completed within 14 months Use one of a safe method of contraception in men and women up to 3 months after the last dose of the vaccine