Patient's informed consent to participation in the study Speaking persian Established diagnosis of Covid-19 by a positive PCR or typical signs of the infection in lung ct scan Absence of depression, anxiety or other psychiatric disorders Absence of mental retardation Negative history of using psychotropic medication in the past 8 weeks No history of hepatic, renal or cardiac disorders BMI<30 Negative history of cigarette or other substance use Admission in non-ICU wards at the beginning of the intervention Absence of melatonin in the therapeutic regimen of the patient Fixed therapeutic regimen Not being pregnant at the time of admission

Patient's informed consent to participation in the study Speaking persian Established diagnosis of Covid-19 by a positive PCR or typical signs of the infection in lung ct scan Absence of depression, anxiety or other psychiatric disorders Absence of mental retardation Negative history of using psychotropic medication in the past 8 weeks No history of hepatic, renal or cardiac disorders BMI<30 Negative history of cigarette or other substance use Admission in non-ICU wards at the beginning of the intervention Absence of melatonin in the therapeutic regimen of the patient Fixed therapeutic regimen Not being pregnant at the time of admission