Definitive diagnosis of COVID-19 based on RT-PCR or/and serological testing, Age >20 years. Diagnosis of pneumonia based on pulmonary CT-Scan. Admitted in the intensive care unit. Signing informed consent and willingness of study participant to accept randomization to any assigned treatment arm.

Definitive diagnosis of COVID-19 based on RT-PCR or/and serological testing, Age >20 years. Diagnosis of pneumonia based on pulmonary CT-Scan. Admitted in the intensive care unit. Signing informed consent and willingness of study participant to accept randomization to any assigned treatment arm.