Created at Source Raw Value Validated value
Jan. 28, 2021, 1 a.m. irct

[{"arm_notes": "", "treatment_id": null, "treatment_name": "TODO PlaceboControl group: The control group receives standard treatment including the following: Oxygen therapy, using a mask or nasal cannula based on the patients' O2 saturation. Corticosteroids (if more than 5 days since the onset of symptoms have passed or SatO2 without adjuvant oxygen is below 90) are prescribed for a maximum of 2 weeks as following: Dexamethasone 6-8 mg/day or Prednisolone 0.5 mg/kg/day (max: 40mg). Anticoagulants, including heparin or enoxaparin: Subcutaneous enoxaparin in patients with GFR above 30:For BMI below 30= 40mg/day subcutaneously, For BMI above 30= 60mg/day subcutaneously or Heparin 5000U, TDS subcutaneously. Due to the lack of conclusive evidence for effectiveness of antiviral therapies in hospitalized patients with COVID-19, one of these antivirals including Lopinavir/Ritonavir, Atazanavir or Remdesivir may be prescribed based on physician\u2019s decision.", "treatment_type": "TODO", "pharmacological_treatment": "Placebo"}, {"arm_notes": "", "treatment_id": null, "treatment_name": "TODO Treatment - DrugsIntervention group: The intervention group, in addition to standarad treatment, receives 80 mg of adalimumab (with the concentration of 40mg/0.8ml) produced by Cinnagen Company (CinnoRA\u00ae) subcutaneously and as a single dose. Standard treatment: Oxygen therapy, using a mask or nasal cannula based on the patients' O2 saturation. Corticosteroids (if more than 5 days since the onset of symptoms have passed or SatO2 without adjuvant oxygen is below 90) are prescribed for a maximum of 2 weeks as following: Dexamethasone 6-8 mg/day or Prednisolone 0.5 mg/kg/day (max: 40mg). Anticoagulants, including heparin or enoxaparin: Subcutaneous enoxaparin in patients with GFR above 30:For BMI below 30=40mg/day subcutaneously, For BMI above 30=60mg/day subcutaneously or Heparin 5000U, TDS subcutaneously. Due to the lack of conclusive evidence for effectiveness of antiviral therapies in hospitalized patients with COVID-19, one of these antivirals including Lopinavir/Ritonavir, Atazanavir or Remdesivir may be prescribed based on physician\u2019s decision.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 27, "treatment_name": "Adalimumab", "treatment_type": "Other targeted therapies", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]