Pregnancy or breast-feeding The physician's decision that the trial is not in the patient's interest Any circumstances that do not allow to follow the treatment protocol easily A history of severe liver disease including cirrhosis or ALT or AST levels more than fives times normal Drugs that are contraindicated with standard treatment or Sofosbuvir-Velpatasvir and cannot be discontinued History of untreated HIV infection or hepatitis C

Pregnancy or breast-feeding The physician's decision that the trial is not in the patient's interest Any circumstances that do not allow to follow the treatment protocol easily A history of severe liver disease including cirrhosis or ALT or AST levels more than fives times normal Drugs that are contraindicated with standard treatment or Sofosbuvir-Velpatasvir and cannot be discontinued History of untreated HIV infection or hepatitis C