Both genders Age ≥18 years at time of signing Informed Consent Form Willing and able to provide written informed consent prior to performing study to any assigned treatment arm Must agree not to enroll in another study of an investigational agent prior to completion of study Will be admitted to Shariati hospital (Tehran), Baharloo (Tehran), Sina (Tehran), Sayyad Shirazi (Gorgan) and not transferred to another hospital Laboratory (RT-PCR) confirmed infection with 2019-nCoV Lung involvement confirmed with chest CT scan Hospitalized patients with: Fever (Oral temperature ≥ 37.8 ℃) and at least one of Respiratory rate >24/min / O2Sat<94% or the Pa02/Fi02 ratio <300mgHg ≤8 days since illness onset

Both genders Age ≥18 years at time of signing Informed Consent Form Willing and able to provide written informed consent prior to performing study to any assigned treatment arm Must agree not to enroll in another study of an investigational agent prior to completion of study Will be admitted to Shariati hospital (Tehran), Baharloo (Tehran), Sina (Tehran), Sayyad Shirazi (Gorgan) and not transferred to another hospital Laboratory (RT-PCR) confirmed infection with 2019-nCoV Lung involvement confirmed with chest CT scan Hospitalized patients with: Fever (Oral temperature ≥ 37.8 ℃) and at least one of Respiratory rate >24/min / O2Sat<94% or the Pa02/Fi02 ratio <300mgHg ≤8 days since illness onset