Age of 18 years or more Elevated C-reactive protein levels Fever or cough or dyspnea SpO2 of 93% or less Confirmed SARS-CoV-2 infection by rt-PCR or radiology PaO2/FiO2 of 300 or less Ability to understand and desire to sign a form of informed consent to participate in the study

Age of 18 years or more Elevated C-reactive protein levels Fever or cough or dyspnea SpO2 of 93% or less Confirmed SARS-CoV-2 infection by rt-PCR or radiology PaO2/FiO2 of 300 or less Ability to understand and desire to sign a form of informed consent to participate in the study