1- Severe case covid disease. 2. Advanced liver disease. 3- Renal dysfunction. 4- History of peptic ulcer. 5. History of allergy to ibuprofen or paracetamol. 6. Vaccinated patient by any type of vaccine either single or twice dose

1- Severe case covid disease. 2. Advanced liver disease. 3- Renal dysfunction. 4- History of peptic ulcer. 5. History of allergy to ibuprofen or paracetamol. 6. Vaccinated patient by any type of vaccine either single or twice dose