Created at Source Raw Value Validated value
Feb. 25, 2022, noon oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: ChAdOx1 nCoV-19 vaccine 0.5 ml intramuscularly: Biological: ChAdOx1 nCoV-19 vaccineA dose of 0.5 ml ChAdOx1 nCoV-19 vaccine 6 months after receiving a double dose of 5x1010vp of ChAdOx1 nCoV-19.Dose: 0.5ml;Frequency: Once;Route of administration: intramuscularly; Duration of therapy: booster dose will be given once.All those cases who have taken two doses of vaccine till 30 June 2021 will be randomised. Allocation will be done in Placebo: Experimental (Vaccine); 1:2 ratio. The intervention will be given in the participants at least after 6 months of the dose of vaccination.All the eligible who have taken 2 doses of ChAdOx1 nCoV- 19 Corona Virus Vaccine (COVISHIELD) vaccine will be enlisted. A computer-generated randomisation procedure in blocks of 15 participant will be used; thus 5 participants in each treatment A; B and C to ensure a stratified random distribution. Two codes will be treatment group and the third will be placebo treatment. The treatment A; B and C will be camouflaged by pasting a permanent wrapper marked with code A; B and C. As we are allocating vaccine and placebo in the ratio 2:1; so for distribution we have made 3 groups; A; B; C. A and B groups receive vaccine; C receives placebo. From statistical point A and B groups are same so for statistical calculation can be clubbed. The eligible patients will be randomly assigned treatment at baseline by means of sequential patient numbers. Treatment allocation will be concealed from all investigators; each patient will be followed up at 90 days/12 weeks if possible. Measures will be taken in the planning and conduct of the trial to reduce the risk that the investigators would be able to identify the treatment received at this end of the study. Investigators coul", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 161, "treatment_name": "Chadox1 ncov-19", "treatment_type": "Non replicating viral vector", "pharmacological_treatment": "Vaccine"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]