Clinical composite endpoint comprising of: <br/ >1 Mortality at Day 28 <br/ >2 Clinical deterioration; defined as progression to a higher ordinal score from enrolment scores of 5 or 6 during the period of 28 days. <br/ >3 Time to recovery by Day 28; defined as time to get to a score of 3 or below in the 8-point ordinalscale plus sustained recovery.Timepoint: 1. Day 1 through Day 28 <br/ >2. Day 1 through Day 28 <br/ >3. Day 1 through Day 28

Clinical composite endpoint comprising of: <br/ >1 Mortality at Day 28 <br/ >2 Clinical deterioration; defined as progression to a higher ordinal score from enrolment scores of 5 or 6 during the period of 28 days. <br/ >3 Time to recovery by Day 28; defined as time to get to a score of 3 or below in the 8-point ordinalscale plus sustained recovery.Timepoint: 1. Day 1 through Day 28 <br/ >2. Day 1 through Day 28 <br/ >3. Day 1 through Day 28