Created at Source Raw Value Validated value
Feb. 25, 2022, noon oms

1 Male or female adults above �18 years. <br/ > 2 Informed consent for participation in the study by patient or their legally acceptable representative. <br/ > 3 Hospitalised patients with COVID-19 infection receiving systemic steroids with scores 5 or 6 on 8-point clinical scale (hospitalised and requiring supplemental oxygen / requiring non-invasive ventilation or use of high-flow oxygen devices but not on invasive mechanical ventilation) <br/ > 4 An inflammatory, phenotype defined by a body temperature greater than 38 °C / 100.4 °F anytime during the last 2 days, OR increased markers of inflammation (CRP � 3 ULN as per local lab) at screening. <br/ > 5 A confirmed virological diagnosis of SARS-CoV2 infection with RT-PCR <br/ > 6 Patients with no known history of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV). <br/ > 7 Women of childbearing potential (WOCP) with negative pregnancy test or are not breastfeeding at screening. <br/ > 8 Males and WOCP agreeing to use adequate contraception (e.g., double barrier contraception) for 130 days from randomisation. <br/ >

1 Male or female adults above �18 years. <br/ > 2 Informed consent for participation in the study by patient or their legally acceptable representative. <br/ > 3 Hospitalised patients with COVID-19 infection receiving systemic steroids with scores 5 or 6 on 8-point clinical scale (hospitalised and requiring supplemental oxygen / requiring non-invasive ventilation or use of high-flow oxygen devices but not on invasive mechanical ventilation) <br/ > 4 An inflammatory, phenotype defined by a body temperature greater than 38 °C / 100.4 °F anytime during the last 2 days, OR increased markers of inflammation (CRP � 3 ULN as per local lab) at screening. <br/ > 5 A confirmed virological diagnosis of SARS-CoV2 infection with RT-PCR <br/ > 6 Patients with no known history of human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV). <br/ > 7 Women of childbearing potential (WOCP) with negative pregnancy test or are not breastfeeding at screening. <br/ > 8 Males and WOCP agreeing to use adequate contraception (e.g., double barrier contraception) for 130 days from randomisation. <br/ >