1) Those who require oxygen (room oxygen saturation of 93% or less )2) Those who do not agree to treatment in hospital3) Those who are taking colchicine4) Those who are taking 10 mg or more of prednisolone daily (or equivalent dose of other glucocorticoids)5) Use of glucocorticoids (orally or intravenously) within the past week.6) Sleep apnea syndrome or suspected sleep apnea syndrome7) Severe diarrhea8) Use of CYP3A4 inhibitor or P-glycoprotein inhibitor9) Liver dysfunction AST or ALT exceeds 5 times the upper limit of normal value10) Renal dysfunction eGFR less than 30mL / min / 1.73m211) Patients with a history of hypersensitivity to the ingredients of this drug12) Pregnant women or women who may be pregnant at the interview

1) Those who require oxygen (room oxygen saturation of 93% or less )2) Those who do not agree to treatment in hospital3) Those who are taking colchicine4) Those who are taking 10 mg or more of prednisolone daily (or equivalent dose of other glucocorticoids)5) Use of glucocorticoids (orally or intravenously) within the past week.6) Sleep apnea syndrome or suspected sleep apnea syndrome7) Severe diarrhea8) Use of CYP3A4 inhibitor or P-glycoprotein inhibitor9) Liver dysfunction AST or ALT exceeds 5 times the upper limit of normal value10) Renal dysfunction eGFR less than 30mL / min / 1.73m211) Patients with a history of hypersensitivity to the ingredients of this drug12) Pregnant women or women who may be pregnant at the interview