1. Patients not willing to be research subjects 2. Patients with comorbid and thyroid diseases 3. Pregnant patients 4. Patients routinely consumed lithium drugs 5. Patients undergoing radioactive iodine treatment 6. Patients allergic to povidone iodine and hydrogen peroxide

1. Patients not willing to be research subjects 2. Patients with comorbid and thyroid diseases 3. Pregnant patients 4. Patients routinely consumed lithium drugs 5. Patients undergoing radioactive iodine treatment 6. Patients allergic to povidone iodine and hydrogen peroxide