1. Those who clearly have a serious acute disease2. Those who have a history of severe hypersensitivity to ingredients in the investigational product3. Those who receive anticoagulation treatment or have thromboembolism, thrombocytopenia or clotting disorder4. Those who have previously diagnosed with immunodeficiency or have any close relatives with congenital immunodeficiency5. Those who have underlying disease such as cardiovascular disease, renal disease, hepatic disease, hematologic disease or developmental disability6. Those who have been vaccinated with the investigational product7. Those who have a history of capillary leak syndrome8. Those who have been vaccinated with non-investigational product in 14 days prior to investigational product 9. Those who have received immunosuppressant (except for topical steroid, and low dose steroid used for less than 14 days) in 6 months prior to investigational product10. Those who are considered inappropriate for the research at PI's (or SI's) discretion other than the above

1. Those who clearly have a serious acute disease2. Those who have a history of severe hypersensitivity to ingredients in the investigational product3. Those who receive anticoagulation treatment or have thromboembolism, thrombocytopenia or clotting disorder4. Those who have previously diagnosed with immunodeficiency or have any close relatives with congenital immunodeficiency5. Those who have underlying disease such as cardiovascular disease, renal disease, hepatic disease, hematologic disease or developmental disability6. Those who have been vaccinated with the investigational product7. Those who have a history of capillary leak syndrome8. Those who have been vaccinated with non-investigational product in 14 days prior to investigational product 9. Those who have received immunosuppressant (except for topical steroid, and low dose steroid used for less than 14 days) in 6 months prior to investigational product10. Those who are considered inappropriate for the research at PI's (or SI's) discretion other than the above