1. Healthy individuals aged 18-59 years as well as 60 years and above who can provide legal identification (males and females are both required). 2. Individuals who are able to understand the contents in the informed consent form and information about the investigational vaccine used in this study, willing to sign the informed consent form, able to use the thermometer, scale as well as fill in the diary card and contact card as required. 3. Individuals who are able to communicate with the investigators, able and willing to understand and comply with all study requirements. 4. For female participants of childbearing potential, effective contraception should be used within 2 weeks prior to participation in this study and the pregnancy test is required to be negative (those with amenorrhea of at least 1 year or surgical sterilization verified by medical records could be exempted from the pregnancy test). Participants should voluntarily agrees to continue using at least one effective methods of contraception for 12 months after full immunization (effective methods include oral contraceptives, injectable or implantable contraceptives, sustained-release topical contraceptives, hormonal patches, intrauterine device, sterilization, abstinence, condoms (for males), diaphragms, cervical caps, etc.). 5. Axillary temperature <37.3? on the day of screening.

1. Healthy individuals aged 18-59 years as well as 60 years and above who can provide legal identification (males and females are both required). 2. Individuals who are able to understand the contents in the informed consent form and information about the investigational vaccine used in this study, willing to sign the informed consent form, able to use the thermometer, scale as well as fill in the diary card and contact card as required. 3. Individuals who are able to communicate with the investigators, able and willing to understand and comply with all study requirements. 4. For female participants of childbearing potential, effective contraception should be used within 2 weeks prior to participation in this study and the pregnancy test is required to be negative (those with amenorrhea of at least 1 year or surgical sterilization verified by medical records could be exempted from the pregnancy test). Participants should voluntarily agrees to continue using at least one effective methods of contraception for 12 months after full immunization (effective methods include oral contraceptives, injectable or implantable contraceptives, sustained-release topical contraceptives, hormonal patches, intrauterine device, sterilization, abstinence, condoms (for males), diaphragms, cervical caps, etc.). 5. Axillary temperature <37.3? on the day of screening.