1. A person who shows severe COVID-19 symptoms and meets at least one of the following conditions at the time of randomization 1.1. Blood oxygen saturation (SpO2) < 94% at room air conditions 1.2. Respiration rate > 30 breaths/min 2. Persons with hypersensitivity to clinical investigational drugs (Justicia procumbens) 3. Patients with gastrointestinal diseases and surgeries that may affect drug absorption, distribution, metabolism, and excretion, current active gastritis, gastrointestinal/rectal bleeding, gastric ulcer, pancreatic dysfunction such as pancreatitis (except for simple appendicectomy or hernia surgery) )factor 4. Those who have received drugs such as antiviral drugs, neutralizing antibody therapy, plasma fraction therapy, and other immune modulators (cytokine therapy, etc.) for the purpose of treating COVID-19 infection within 28 days prior to screening (however, sufficient wash-out period) After this, you can participate in clinical trials) However, those who started administering drugs approved or approved for emergency use by domestic regulatory authorities as a treatment for COVID-19 within 24 hours of randomization can register, and for details, follow Section 8.3.2 of the main text. 5. Those who received any vaccinations within 14 days of randomization 6. Renal impairment (serum creatinine > 1.5 times the upper limit of organ normal) 7. Hepatic impairment (ALT or AST > 3 times the upper limit of organ normal) 8. Persons with viral diseases other than COVID-19 (HIV, HBV, HCV, etc.) that require administration of other antiviral drugs 9. Those who require mechanical ventilation (eg, non invasive ventilation, invasive mechanical ventilation, extracorporeal membrane oxygenation, etc.) 10. Patients with chronic underlying diseases who are unsuitable for clinical trial participation (uncontrolled diabetes, chronic kidney disease, chronic liver disease, chronic lung disease, chronic cardiovascular disease, blood cancer, chemotherapy cancer patients, patients taking immunosuppressants, etc.) 11. Pregnant women or breastfeeding mothers 12. Women and men of childbearing potential who plan to become pregnant or do not intend to use the appropriate contraceptive methods 13. A person who has participated in another clinical trial/medical device clinical trial within 28 days from the date of signing the consent form and has received/administered/treated clinical investigational drug/medical device 14. A person who has been determined that it is inappropriate to participate in this study for any other reasons by the investigator.

1. A person who shows severe COVID-19 symptoms and meets at least one of the following conditions at the time of randomization 1.1. Blood oxygen saturation (SpO2) < 94% at room air conditions 1.2. Respiration rate > 30 breaths/min 2. Persons with hypersensitivity to clinical investigational drugs (Justicia procumbens) 3. Patients with gastrointestinal diseases and surgeries that may affect drug absorption, distribution, metabolism, and excretion, current active gastritis, gastrointestinal/rectal bleeding, gastric ulcer, pancreatic dysfunction such as pancreatitis (except for simple appendicectomy or hernia surgery) )factor 4. Those who have received drugs such as antiviral drugs, neutralizing antibody therapy, plasma fraction therapy, and other immune modulators (cytokine therapy, etc.) for the purpose of treating COVID-19 infection within 28 days prior to screening (however, sufficient wash-out period) After this, you can participate in clinical trials) However, those who started administering drugs approved or approved for emergency use by domestic regulatory authorities as a treatment for COVID-19 within 24 hours of randomization can register, and for details, follow Section 8.3.2 of the main text. 5. Those who received any vaccinations within 14 days of randomization 6. Renal impairment (serum creatinine > 1.5 times the upper limit of organ normal) 7. Hepatic impairment (ALT or AST > 3 times the upper limit of organ normal) 8. Persons with viral diseases other than COVID-19 (HIV, HBV, HCV, etc.) that require administration of other antiviral drugs 9. Those who require mechanical ventilation (eg, non invasive ventilation, invasive mechanical ventilation, extracorporeal membrane oxygenation, etc.) 10. Patients with chronic underlying diseases who are unsuitable for clinical trial participation (uncontrolled diabetes, chronic kidney disease, chronic liver disease, chronic lung disease, chronic cardiovascular disease, blood cancer, chemotherapy cancer patients, patients taking immunosuppressants, etc.) 11. Pregnant women or breastfeeding mothers 12. Women and men of childbearing potential who plan to become pregnant or do not intend to use the appropriate contraceptive methods 13. A person who has participated in another clinical trial/medical device clinical trial within 28 days from the date of signing the consent form and has received/administered/treated clinical investigational drug/medical device 14. A person who has been determined that it is inappropriate to participate in this study for any other reasons by the investigator.

1. A person who shows severe COVID-19 symptoms and meets at least one of the following conditions at the time of randomization 1.1. Blood oxygen saturation (SpO2) < 94% at room air conditions 1.2. Respiration rate > 30 breaths/min 2. Persons with hypersensitivity to clinical investigational drugs (Justicia procumbens) 3. Patients with gastrointestinal diseases and surgeries that may affect drug absorption, distribution, metabolism, and excretion, current active gastritis, gastrointestinal/rectal bleeding, gastric ulcer, pancreatic dysfunction such as pancreatitis (except for simple appendicectomy or hernia surgery) )factor 4. Those who have received drugs such as antiviral drugs, neutralizing antibody therapy, plasma fraction therapy, and other immune modulators (cytokine therapy, etc.) for the purpose of treating COVID-19 infection within 28 days prior to screening (however, sufficient wash-out period) After this, you can participate in clinical trials) 5. Those who received any vaccinations within 14 days of randomization 6. Renal impairment (serum creatinine > 1.5 times the upper limit of organ normal) 7. Hepatic impairment (ALT or AST > 3 times the upper limit of organ normal) 8. Persons with viral diseases other than COVID-19 (HIV, HBV, HCV, etc.) that require administration of other antiviral drugs 9. Those who require mechanical ventilation (eg, non invasive ventilation, invasive mechanical ventilation, extracorporeal membrane oxygenation, etc.) 10. Patients with chronic underlying diseases who are unsuitable for clinical trial participation (uncontrolled diabetes, chronic kidney disease, chronic liver disease, chronic lung disease, chronic cardiovascular disease, blood cancer, chemotherapy cancer patients, patients taking immunosuppressants, etc.) 11. Pregnant women or breastfeeding mothers 12. Women and men of childbearing potential who plan to become pregnant or do not intend to use the appropriate contraceptive methods 13. A person who has participated in another clinical trial/medical device clinical trial within 28 days from the date of signing the consent form and has received/administered/treated clinical investigational drug/medical device 14. A person who has been determined that it is inappropriate to participate in this study for any other reasons by the investigator.

1. A person who shows severe COVID-19 symptoms and meets at least one of the following conditions at the time of randomization 1.1. Blood oxygen saturation (SpO2) < 94% at room air conditions 1.2. Respiration rate > 30 breaths/min 2. Persons with hypersensitivity to clinical investigational drugs (Justicia procumbens) 3. Patients with gastrointestinal diseases and surgeries that may affect drug absorption, distribution, metabolism, and excretion, current active gastritis, gastrointestinal/rectal bleeding, gastric ulcer, pancreatic dysfunction such as pancreatitis (except for simple appendicectomy or hernia surgery) )factor 4. Those who have received drugs such as antiviral drugs, neutralizing antibody therapy, plasma fraction therapy, and other immune modulators (cytokine therapy, etc.) for the purpose of treating COVID-19 infection within 28 days prior to screening (however, sufficient wash-out period) After this, you can participate in clinical trials) 5. Those who received any vaccinations within 14 days of randomization 6. Renal impairment (serum creatinine > 1.5 times the upper limit of organ normal) 7. Hepatic impairment (ALT or AST > 3 times the upper limit of organ normal) 8. Persons with viral diseases other than COVID-19 (HIV, HBV, HCV, etc.) that require administration of other antiviral drugs 9. Those who require mechanical ventilation (eg, non invasive ventilation, invasive mechanical ventilation, extracorporeal membrane oxygenation, etc.) 10. Patients with chronic underlying diseases who are unsuitable for clinical trial participation (uncontrolled diabetes, chronic kidney disease, chronic liver disease, chronic lung disease, chronic cardiovascular disease, blood cancer, chemotherapy cancer patients, patients taking immunosuppressants, etc.) 11. Pregnant women or breastfeeding mothers 12. Women and men of childbearing potential who plan to become pregnant or do not intend to use the appropriate contraceptive methods 13. A person who has participated in another clinical trial/medical device clinical trial within 28 days from the date of signing the consent form and has received/administered/treated clinical investigational drug/medical device 14. A person who has been determined that it is inappropriate to participate in this study for any other reasons by the investigator.