1. Severe vomiting and difficulty in taking or ingestion of oral medication, 2. Pregnant and lactating women, 3. People with mental illness and cognitive impairment, 4. Subjects received antiviral drugs (including interferon-alpha, ribavirin, chloroquine phosphate, Abidol, remdesivir, lopinavir/ritonavir, monoclonal antibodies) in the week before admission, 5. Cases of respiratory failure requiring mechanical ventilation, 6. There were cases of shock, 7. ICU care is required for other organ failure, 8. Patients who were clinically predicted to have no hope of survival and were placed on hospice care only, or those who were in a deep coma and did not respond to supportive treatment within three hours of admission.

1. Severe vomiting and difficulty in taking or ingestion of oral medication, 2. Pregnant and lactating women, 3. People with mental illness and cognitive impairment, 4. Subjects received antiviral drugs (including interferon-alpha, ribavirin, chloroquine phosphate, Abidol, remdesivir, lopinavir/ritonavir, monoclonal antibodies) in the week before admission, 5. Cases of respiratory failure requiring mechanical ventilation, 6. There were cases of shock, 7. ICU care is required for other organ failure, 8. Patients who were clinically predicted to have no hope of survival and were placed on hospice care only, or those who were in a deep coma and did not respond to supportive treatment within three hours of admission.