Created at Source Raw Value Validated value
Oct. 13, 2021, 11:30 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Regimen of morning subcutaneous administration of Isophane insulin with basal bolus insulin (BBI). Isophane will be added to a BBI regimen at 20% of the calculated total daily dose (TDD) if the highest blood glucose (BG) is 12-16 mmol/L or 30% of TDD if highest BG is >16 mmol/L. The TDD will be determined on the basis of pre-existing insulin therapy. Participants not on pre-existing insulin (BBI or premixed) will receive BBI at a TDD of 0.5 units/kg or 0.3 units/kg if BG 12-16 mmol/L; age greater than or equal to 70; or chronic kidney disease stage 3.The intervention will commence from the time of recognition of hyperglycaemia following commencement of dexamethasone therapy; until one of the following occurs: cessation of dexamethasone; change to a different diabetes medication regimen (based on clinical decision); discharge from hospital; transfer to the intensive care unit; decision for palliation.Insulin administration will be recorded for the purpose of monitoring adherence to the protocol and insulin usage as a result of the protocol.", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 1981, "treatment_name": "Isophane insulin", "treatment_type": "Hormones", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]