1) Age between 3 and 18 years at the time of inclusion.2) General physical examination and by appliances without alterations at the time of inclusion.3) Nutritional assessment: weight / height ratio between 10 and 90 percentile (for children between 3 and 9 years of age). Body Mass Index (BMI) for the age between 10 and 90 percentile for adolescents between 10 and 18 years old, according to the cut-off points for the Cuban pediatric population.4) Voluntariness of both parents (or legal guardian) by signing the informed consent, as well as informed consent for adolescents aged =12 years.

1) Age between 3 and 18 years at the time of inclusion.2) General physical examination and by appliances without alterations at the time of inclusion.3) Nutritional assessment: weight / height ratio between 10 and 90 percentile (for children between 3 and 9 years of age). Body Mass Index (BMI) for the age between 10 and 90 percentile for adolescents between 10 and 18 years old, according to the cut-off points for the Cuban pediatric population.4) Voluntariness of both parents (or legal guardian) by signing the informed consent, as well as informed consent for adolescents aged =12 years.