1. Male or female subjects having age 18 years to 60 years. <br/ >2. Subject and/or his/her legally accepted representative willing to give written informed consent. <br/ >3. Subjects having Critical COVID-19 with ARDS/respiratory failure requiring either mechanical ventilation, non-invasive <br/ >ventilation, or high flow rate nasal cannula at minimum 20L flow and 50% FIO2. <br/ >(Severe cases of COVID-19 as per MoH & FW guidelines on â??Clinical Management Protocol: COVID-19â?? as updated from <br/ >time to time. Case of severe COVID-19 defined as presence of clinical features of pneumonia (fever, cough, dyspnea and/ or hypoxia) with any of the following: <br/ >ï?· SpO2 <90% on room air <br/ >ï?· Severe respiratory distress <br/ >ï?· Respiratory rate more than 30 per minute

1. Male or female subjects having age 18 years to 60 years. <br/ >2. Subject and/or his/her legally accepted representative willing to give written informed consent. <br/ >3. Subjects having Critical COVID-19 with ARDS/respiratory failure requiring either mechanical ventilation, non-invasive <br/ >ventilation, or high flow rate nasal cannula at minimum 20L flow and 50% FIO2. <br/ >(Severe cases of COVID-19 as per MoH & FW guidelines on â??Clinical Management Protocol: COVID-19â?? as updated from <br/ >time to time. Case of severe COVID-19 defined as presence of clinical features of pneumonia (fever, cough, dyspnea and/ or hypoxia) with any of the following: <br/ >ï?· SpO2 <90% on room air <br/ >ï?· Severe respiratory distress <br/ >ï?· Respiratory rate more than 30 per minute

1. Male or female subjects having age 18 years to 60 years. <br/ >2. Subject and/or his/her legally accepted representative willing to give written informed consent. <br/ >3. Subjects having Critical COVID-19 with ARDS/respiratory failure requiring either mechanical ventilation, non-invasive <br/ >ventilation, or high flow rate nasal cannula at minimum 20L flow and 50% FIO2. <br/ >(Severe cases of COVID-19 as per MoH & FW guidelines on â??Clinical Management Protocol: COVID-19â?? as updated from <br/ >time to time. Case of severe COVID-19 defined as presence of clinical features of pneumonia (fever, cough, dyspnea and/ or hypoxia) with any of the following: <br/ >ï?· SpO2 <90% on room air <br/ >ï?· Severe respiratory distress <br/ >ï?· Respiratory rate more than 30 per minute

1. Male or female subjects having age 18 years to 60 years. <br/ >2. Subject and/or his/her legally accepted representative willing to give written informed consent. <br/ >3. Subjects having Critical COVID-19 with ARDS/respiratory failure requiring either mechanical ventilation, non-invasive <br/ >ventilation, or high flow rate nasal cannula at minimum 20L flow and 50% FIO2. <br/ >(Severe cases of COVID-19 as per MoH & FW guidelines on â??Clinical Management Protocol: COVID-19â?? as updated from <br/ >time to time. Case of severe COVID-19 defined as presence of clinical features of pneumonia (fever, cough, dyspnea and/ or hypoxia) with any of the following: <br/ >ï?· SpO2 <90% on room air <br/ >ï?· Severe respiratory distress <br/ >ï?· Respiratory rate more than 30 per minute