1.Age 40 years or more and 2. Patients confirmed to have COVID-19 based on a positive RT_PCR for SARS CoV-2 and have been admitted to the hospital and 3. patients with any of a. PaO2/FiO2 between 100mmHg and 300mmHg or b. Respiratory rate >24per min or more, breathlessness or c. SpO2 <94% on room air and 4. Lung parenchymal involvement at baseline CT scan

1.Age 40 years or more and 2. Patients confirmed to have COVID-19 based on a positive RT_PCR for SARS CoV-2 and have been admitted to the hospital and 3. patients with any of a. PaO2/FiO2 between 100mmHg and 300mmHg or b. Respiratory rate >24per min or more, breathlessness or c. SpO2 <94% on room air and 4. Lung parenchymal involvement at baseline CT scan

1.Age 40 years or more and 2. Patients confirmed to have COVID-19 based on a positive RT_PCR for SARS CoV-2 and have been admitted to the hospital and 3. patients with any of a. PaO2/FiO2 between 100mmHg and 300mmHg or b. Respiratory rate >24per min or more, breathlessness or c. SpO2 <94% on room air and 4. Lung parenchymal involvement at baseline CT scan

1.Age 40 years or more and 2. Patients confirmed to have COVID-19 based on a positive RT_PCR for SARS CoV-2 and have been admitted to the hospital and 3. patients with any of a. PaO2/FiO2 between 100mmHg and 300mmHg or b. Respiratory rate >24per min or more, breathlessness or c. SpO2 <94% on room air and 4. Lung parenchymal involvement at baseline CT scan