Created at Source Raw Value Validated value
Nov. 26, 2021, 10:30 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Low Dose Radiation therapy in addition to standard of care as per ICMR guidelines: Low dose radiation to a dose of 0.5Gy in single fraction with AP-PA fields using CT based planning on a Linear Accelerator in addition to pharmacological therapy as per ICMR guidelines;India . Dexamethasone 6mg IV Once daily for 10 days (Alternative: Methylprednisolone 80mg IV BD for 10 days) Enoxiparin 60mgs/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response;Vitamin D 60;000U /week; Vitamin C 1500 mg/day; Zinc; Paracetamol; Anti-tussives; Antibiotics; Oxygen supplementation. Adjunctive therapies : IV thiamine;IV vitamin C; N acetyl cysteine; Ulinastatin; Sepsivac (mycobacterium w); high dose statins. Salvage therapies : Pulse therapy of steroids; Cytosorb-hemoperfusion; Pirfenidone; Alteplase. The pharmacologic therapy is individualized on a case by case basisControl Intervention1: Standard of care as per ICMR guidelines: Pharmacological therapy as per ICMR guidelines;India. Dexamethasone 6mg IV Once daily for 10 days (Alternative: Methylprednisolone 80mg IV BD for 10 days) Enoxiparin 60mgs/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response;Vitamin D 60;000U /week; Vitamin C 1500 mg/day; Zinc; Paracetamol; Anti-tussives; Antibiotics; Oxygen supplementation. Adjunctive therapies : IV thiamine;IV vitamin C; N acetyl cysteine; Ulinastatin; Sepsivac (mycobacterium w); high dose statins. Salvage therapies : Pulse therapy of steroids; Cytosorb-hemoperfusion; Pirfenidone;Alteplase. Th", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "", "treatment_id": 746, "treatment_name": "Low dose radiation therapy", "treatment_type": "Radiation therapy", "pharmacological_treatment": "Non pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2188, "treatment_name": "Standard of care", "treatment_type": "Standard of care", "pharmacological_treatment": "Standard of care"}]

Nov. 13, 2021, 5:33 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "N/A", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

Sept. 8, 2021, 1:30 a.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Intervention1: Low Dose Radiation therapy in addition to standard of care as per ICMR guidelines: Low dose radiation to a dose of 0.5Gy in single fraction with AP-PA fields using CT based planning on a Linear Accelerator in addition to pharmacological therapy as per ICMR guidelines;India . Dexamethasone 6mg IV Once daily for 10 days (Alternative: Methylprednisolone 80mg IV BD for 10 days) Enoxiparin 60mgs/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response;Vitamin D 60;000U /week; Vitamin C 1500 mg/day; Zinc; Paracetamol; Anti-tussives; Antibiotics; Oxygen supplementation. Adjunctive therapies : IV thiamine;IV vitamin C; N acetyl cysteine; Ulinastatin; Sepsivac (mycobacterium w); high dose statins. Salvage therapies : Pulse therapy of steroids; Cytosorb-hemoperfusion; Pirfenidone; Alteplase. The pharmacologic therapy is individualized on a case by case basisControl Intervention1: Standard of care as per ICMR guidelines: Pharmacological therapy as per ICMR guidelines;India. Dexamethasone 6mg IV Once daily for 10 days (Alternative: Methylprednisolone 80mg IV BD for 10 days) Enoxiparin 60mgs/c Once Daily for 5 days (dose adjusted based on D-dimer levels); Remdesvir 200mg IV Once daily on day 1 followed by 100mg IV Once daily for next 4 days; further continuance based on clinical response;Vitamin D 60;000U /week; Vitamin C 1500 mg/day; Zinc; Paracetamol; Anti-tussives; Antibiotics; Oxygen supplementation. Adjunctive therapies : IV thiamine;IV vitamin C; N acetyl cysteine; Ulinastatin; Sepsivac (mycobacterium w); high dose statins. Salvage therapies : Pulse therapy of steroids; Cytosorb-hemoperfusion; Pirfenidone;Alteplase. Th", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]