inclusion criteria: 1. willing to provide written informed consent 2. willing to comply with all study procedures and be available for the duration of the study 3. male or female ≥ 18 years of age 4. sars-cov-2 infection (covid-19) within the past 10 d documented by laboratory test (nucleic acid test (nat) or reverse transcriptase-polymerase chain reaction (rt-pcr)) 5. currently hospitalized 6. symptoms of acute respiratory infection (at least one of the following: cough, fever \> 37.5°c, dyspnea, sore throat, anosmia), 7. radiographic evidence of pulmonary infiltrates 8. requiring supplemental oxygen or the peripheral capillary oxygenation saturation (spo2) \< 94% on room air at screening 9. elevated d-dimer \> 0.49 mg/l 10. negative pregnancy test for females of childbearing potential

inclusion criteria: 1. willing to provide written informed consent 2. willing to comply with all study procedures and be available for the duration of the study 3. male or female ≥ 18 years of age 4. sars-cov-2 infection (covid-19) within the past 10 d documented by laboratory test (nucleic acid test (nat) or reverse transcriptase-polymerase chain reaction (rt-pcr)) 5. currently hospitalized 6. symptoms of acute respiratory infection (at least one of the following: cough, fever \> 37.5°c, dyspnea, sore throat, anosmia), 7. radiographic evidence of pulmonary infiltrates 8. requiring supplemental oxygen or the peripheral capillary oxygenation saturation (spo2) \< 94% on room air at screening 9. elevated d-dimer \> 0.49 mg/l 10. negative pregnancy test for females of childbearing potential

inclusion criteria: willing to provide written informed consent willing to comply with all study procedures and be available for the duration of the study male or female ≥ 18 years of age sars-cov-2 infection (covid-19) within the past 10 d documented by laboratory test (nucleic acid test (nat) or reverse transcriptase-polymerase chain reaction (rt-pcr)) currently hospitalized symptoms of acute respiratory infection (at least one of the following: cough, fever > 37.5°c, dyspnea, sore throat, anosmia), radiographic evidence of pulmonary infiltrates requiring supplemental oxygen or the peripheral capillary oxygenation saturation (spo2) < 94% on room air at screening elevated d-dimer > 0.49 mg/l negative pregnancy test for females of childbearing potential

inclusion criteria: willing to provide written informed consent willing to comply with all study procedures and be available for the duration of the study male or female ≥ 18 years of age sars-cov-2 infection (covid-19) within the past 10 d documented by laboratory test (nucleic acid test (nat) or reverse transcriptase-polymerase chain reaction (rt-pcr)) currently hospitalized symptoms of acute respiratory infection (at least one of the following: cough, fever > 37.5°c, dyspnea, sore throat, anosmia), radiographic evidence of pulmonary infiltrates requiring supplemental oxygen or the peripheral capillary oxygenation saturation (spo2) < 94% on room air at screening elevated d-dimer > 0.49 mg/l negative pregnancy test for females of childbearing potential

inclusion criteria: 1. willing to provide written informed consent 2. willing to comply with all study procedures and be available for the duration of the study 3. male or female ≥ 18 years of age 4. sars-cov-2 infection (covid-19) within the past 10 d documented by laboratory test (nucleic acid test (nat) or reverse transcriptase-polymerase chain reaction (rt-pcr)) 5. currently hospitalized 6. symptoms of acute respiratory infection (at least one of the following: cough, fever > 37.5°c, dyspnea, sore throat, anosmia), 7. radiographic evidence of pulmonary infiltrates 8. requiring supplemental oxygen or the peripheral capillary oxygenation saturation (spo2) < 94% on room air at screening 9. elevated d-dimer > 0.49 mg/l 10. negative pregnancy test for females of childbearing potential

inclusion criteria: 1. willing to provide written informed consent 2. willing to comply with all study procedures and be available for the duration of the study 3. male or female ≥ 18 years of age 4. sars-cov-2 infection (covid-19) within the past 10 d documented by laboratory test (nucleic acid test (nat) or reverse transcriptase-polymerase chain reaction (rt-pcr)) 5. currently hospitalized 6. symptoms of acute respiratory infection (at least one of the following: cough, fever > 37.5°c, dyspnea, sore throat, anosmia), 7. radiographic evidence of pulmonary infiltrates 8. requiring supplemental oxygen or the peripheral capillary oxygenation saturation (spo2) < 94% on room air at screening 9. elevated d-dimer > 0.49 mg/l 10. negative pregnancy test for females of childbearing potential