Created at Source Raw Value Validated value
Sept. 1, 2021, 11 p.m. oms

[{"arm_notes": "", "treatment_id": null, "treatment_name": "Study setting:Intermediate care centre for the patients with SARS CoV- 2 at Arachchikanda; Galle District; Sri LankaRandomization method:Patients would be randomized to two equal groups with computer derived random number generating table by a third party. This third party does not include any investigator or staff in the Intermediate care center (ICC) At the time of enrollment of participants to the study the third party will be contacted by the staff of the ICC to assign the patient to the treatment or placebo group. The assignment will be recorded by the third party and would not expose concealed allocation to the researchers until the analysis of the data would be completed. The only exception would be if the Physician in charge of the patient/s request the randomization for placebo or drug for the management of a complication suspected to be due to the drug; then it would be divulged to the physician by the third party.Intervention group: On day 1; HHT would be administered twice daily at a dosage of 0.3 mg (half of the calculated dose) in 3 ml of normal saline; if patients could tolerate the dose; 0.6mg in 3 ml of normal saline would be administered twice per day for 5 days from day 2 onwards. If the CT value of day 5 indicates viral clearance with a negative PCR; HHT administration would be discontinued and if not; it will be continued until day 7 is completed. Control group: 3 ml of 0.9% saline twice daily would be administered for 7 consecutive days as placebo to the control groupStandard care will be provided to both groups. Standard care at ICC is the care stipulated in the guideline of the Ministry of Health on management of asymptomatic or minimally symptomatic patients with COVID-19 infection. This includes paraceta", "treatment_type": "TODO", "pharmacological_treatment": "TODO"}]

[{"arm_notes": "nebulized", "treatment_id": 1973, "treatment_name": "Omacetaxine mepesuccinate", "treatment_type": "Others pharmacological treatment", "pharmacological_treatment": "Pharmacological treatment"}, {"arm_notes": "", "treatment_id": 2187, "treatment_name": "Placebo", "treatment_type": "Placebo", "pharmacological_treatment": "Placebo"}]