• Pregnancy (confirmed or suspected with a history of a missing menstrual period for more than a week) • Breast-feeding mothers • Adolescents below 18 years • HIV co-infection • Patients who are known to have allergy to ivermectin or anthelminths • Patients with severe disease as indicated by SpO2 <=93% on room air at sea level or PaO2/FiO2 < 300, respiratory rate >=30 per minute, heart rate >=125 per minute • Patients with critical disease ie. those who require mechanical ventilation or anticipated impending need for mechanical ventilation • Those who have received the vaccine *. A patient recruited in any other trials simultaneously

• Pregnancy (confirmed or suspected with a history of a missing menstrual period for more than a week) • Breast-feeding mothers • Adolescents below 18 years • HIV co-infection • Patients who are known to have allergy to ivermectin or anthelminths • Patients with severe disease as indicated by SpO2 <=93% on room air at sea level or PaO2/FiO2 < 300, respiratory rate >=30 per minute, heart rate >=125 per minute • Patients with critical disease ie. those who require mechanical ventilation or anticipated impending need for mechanical ventilation • Those who have received the vaccine *. A patient recruited in any other trials simultaneously