1) Subjects with acute febrile or infectious disease at the time of the vaccine application or in the 7 days prior to its administration. 2) Subjects meeting any of the following criteria: a) Previous or current history of SARS-CoV 2 infection. b) Being declared in the contact or suspect category at the time of inclusion. 3) Subjects with a history of hypersensitivity to Thimerosal or any of the components of the formulations. 4) Subjects with a history of having been immunized with a vaccine against SARS-CoV 2. 5) Subjects with a history of having received a vaccine from the Cuban immunization scheme, in a period of less than 30 days prior to the administration of the investigational product . 6) Use of any investigational product in the 30 days prior to immunization. 7) Application of vaccines containing tetanus toxoid in the last 3 months. 8) Subjects with a history of major congenital malformations (defects that have an important functional compromise for the individual's life, have medical consequences and require early attention, sometimes urgently). 9) Primary or secondary immune system disease. 10) History of neoplastic disease. 11) History of severe allergic reactions. 12) Treatment with immunomodulators in the last 30 days (eg steroids (except topical and inhaled), Interferon, Immunoferon, Nasalferon, Transfer Factor, monoclonal antibody, Biomodulin T, any ganmaglobulin, Heberferon, Thymosin, Levamisole). 13) Subjects with a history of Convulsive Disease. 14) History of treatment with blood products such as blood cell, plasma, whole blood or platelet concentrate transfusions in the last 4 months. 15) Splenectomy or splenic dysfunction. 16) Pregnancy or lactation (a pregnancy test will be carried out before inclusion and administration of each dose to all girls and adolescents who menstruate). 17) Subjects with tattoos in the deltoid region of both arms. 18) Subjects with a history of HIV1 + 2 antibodies, hepatitis C antibodies, hepatitis B virus surface antigen, or VDRL serology. 19) History of psychoactive substance use in the last 6 months.

1) Subjects with acute febrile or infectious disease at the time of the vaccine application or in the 7 days prior to its administration. 2) Subjects meeting any of the following criteria: a) Previous or current history of SARS-CoV 2 infection. b) Being declared in the contact or suspect category at the time of inclusion. 3) Subjects with a history of hypersensitivity to Thimerosal or any of the components of the formulations. 4) Subjects with a history of having been immunized with a vaccine against SARS-CoV 2. 5) Subjects with a history of having received a vaccine from the Cuban immunization scheme, in a period of less than 30 days prior to the administration of the investigational product . 6) Use of any investigational product in the 30 days prior to immunization. 7) Application of vaccines containing tetanus toxoid in the last 3 months. 8) Subjects with a history of major congenital malformations (defects that have an important functional compromise for the individual's life, have medical consequences and require early attention, sometimes urgently). 9) Primary or secondary immune system disease. 10) History of neoplastic disease. 11) History of severe allergic reactions. 12) Treatment with immunomodulators in the last 30 days (eg steroids (except topical and inhaled), Interferon, Immunoferon, Nasalferon, Transfer Factor, monoclonal antibody, Biomodulin T, any ganmaglobulin, Heberferon, Thymosin, Levamisole). 13) Subjects with a history of Convulsive Disease. 14) History of treatment with blood products such as blood cell, plasma, whole blood or platelet concentrate transfusions in the last 4 months. 15) Splenectomy or splenic dysfunction. 16) Pregnancy or lactation (a pregnancy test will be carried out before inclusion and administration of each dose to all girls and adolescents who menstruate). 17) Subjects with tattoos in the deltoid region of both arms. 18) Subjects with a history of HIV1 + 2 antibodies, hepatitis C antibodies, hepatitis B virus surface antigen, or VDRL serology. 19) History of psychoactive substance use in the last 6 months.